Functional significance of the DNA curvature located near a promoter: an analysis using the beta-lactamase promoter of pUC19.

Y. Hirota, Takashi Ohyama

Research output: Contribution to journalArticle

Abstract

The upstream region of the beta-lactamase promoter of pUC19 has a DNA curvature. Whether the curvature plays some role in the transcription from the promoter or not has been studied. The overall three-dimensional structure of the region containing the promoter and the curvature seems to play some significant role in the transcription of the gene. Functional significance of the DNA curvature located in the vicinity of a promoter is discussed.

Original languageEnglish
Pages (from-to)117-118
Number of pages2
JournalNucleic acids symposium series
Issue number25
Publication statusPublished - 1991
Externally publishedYes

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beta-Lactamases
DNA
Genetic Promoter Regions
Genes

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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abstract = "The upstream region of the beta-lactamase promoter of pUC19 has a DNA curvature. Whether the curvature plays some role in the transcription from the promoter or not has been studied. The overall three-dimensional structure of the region containing the promoter and the curvature seems to play some significant role in the transcription of the gene. Functional significance of the DNA curvature located in the vicinity of a promoter is discussed.",
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