Functionalization of ultradispersed diamond for DNA detection

Jung Hoon Yang, Yoshikazu Nakano, Yasunori Murakami, Kwang Soup Song, Hiroshi Kawarada

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Functionalization of nanoparticles and immobilization of biomolecules on nanoparticles are important techniques for various applications in biotechnology. For application in the biomedical field, the surface of ultradispersed diamond (UDD) is immobilized with amino-terminated DNA after functionalizing carboxylic or amino group on the UDD surface. The characterized surface of UDD, carboxylated UDD, and aminated UDD were analyzed by DRIFT spectroscopy. In addition, hybridization with Cy-5 labeled target DNA was clearly observed on functionalized UDD by fluorescence microscopy.

Original languageEnglish
Pages (from-to)69-75
Number of pages7
JournalJournal of Nanoparticle Research
Volume10
Issue numberSUPPL. 1
DOIs
Publication statusPublished - 2008 Dec 1

Keywords

  • Amination
  • Carboxylation
  • DNA immobilization
  • Functionalization
  • Nanomedicine
  • Ultradispersed diamond

ASJC Scopus subject areas

  • Bioengineering
  • Atomic and Molecular Physics, and Optics
  • Chemistry(all)
  • Modelling and Simulation
  • Materials Science(all)
  • Condensed Matter Physics

Fingerprint Dive into the research topics of 'Functionalization of ultradispersed diamond for DNA detection'. Together they form a unique fingerprint.

  • Cite this