Fundamental study on property change of human blood in ELF electric field exposure III-detection of aggregability change in in vitro exposure

Miki Kanemaki, Hisae O. Shimizu, Masataka Kitama, Masaji Yamashita, Hiroko Miura, Koichi Shimizu

Research output: Contribution to journalArticle

Abstract

In the study of biological effects of ELF electric field, we found that the blood flow changes when the field is exposed to our body. The aggregability of red blood cells (RBC’s) in vivo increases right after the field exposure. To elucidate this phenomenon, an experimental study was conducted. Electric field was applied to the blood sample on a slide glass using insulated metal electrodes to make the current density 100 mA/m2 which simulates the current induced inside an adult body with a therapeutic instrument of electric field exposure. As a result, the ratio of the aggregated RBC’s increased about 25% in the field exposure. Through this study, the change in the RBC aggregability was confirmed in the well-controlled in vitro measurement. This suggests the possibility that the blood property change is caused not by the physiological change but by the physical change that is observable in the in vitro condition.

Original languageEnglish
Pages (from-to)1-2
Number of pages2
JournalTransactions of Japanese Society for Medical and Biological Engineering
Volume54
Issue numberPROC
Publication statusPublished - 2016
Externally publishedYes

Fingerprint

Blood
Electric fields
Induced currents
Current density
Cells
Glass
Electrodes
Metals

Keywords

  • Aggregability
  • Biological effects
  • Blood flow
  • ELF electric field
  • Induced current
  • Red blood cells (RBC’s)

ASJC Scopus subject areas

  • Biomedical Engineering

Cite this

Fundamental study on property change of human blood in ELF electric field exposure III-detection of aggregability change in in vitro exposure. / Kanemaki, Miki; Shimizu, Hisae O.; Kitama, Masataka; Yamashita, Masaji; Miura, Hiroko; Shimizu, Koichi.

In: Transactions of Japanese Society for Medical and Biological Engineering, Vol. 54, No. PROC, 2016, p. 1-2.

Research output: Contribution to journalArticle

@article{b08bb5ba08894e34a20ca168aca2b707,
title = "Fundamental study on property change of human blood in ELF electric field exposure III-detection of aggregability change in in vitro exposure",
abstract = "In the study of biological effects of ELF electric field, we found that the blood flow changes when the field is exposed to our body. The aggregability of red blood cells (RBC’s) in vivo increases right after the field exposure. To elucidate this phenomenon, an experimental study was conducted. Electric field was applied to the blood sample on a slide glass using insulated metal electrodes to make the current density 100 mA/m2 which simulates the current induced inside an adult body with a therapeutic instrument of electric field exposure. As a result, the ratio of the aggregated RBC’s increased about 25{\%} in the field exposure. Through this study, the change in the RBC aggregability was confirmed in the well-controlled in vitro measurement. This suggests the possibility that the blood property change is caused not by the physiological change but by the physical change that is observable in the in vitro condition.",
keywords = "Aggregability, Biological effects, Blood flow, ELF electric field, Induced current, Red blood cells (RBC’s)",
author = "Miki Kanemaki and Shimizu, {Hisae O.} and Masataka Kitama and Masaji Yamashita and Hiroko Miura and Koichi Shimizu",
year = "2016",
language = "English",
volume = "54",
pages = "1--2",
journal = "BME = Bio medical engineering / henshu, Nihon ME Gakkai",
issn = "1347-443X",
publisher = "Nihon M E Gakkai",
number = "PROC",

}

TY - JOUR

T1 - Fundamental study on property change of human blood in ELF electric field exposure III-detection of aggregability change in in vitro exposure

AU - Kanemaki, Miki

AU - Shimizu, Hisae O.

AU - Kitama, Masataka

AU - Yamashita, Masaji

AU - Miura, Hiroko

AU - Shimizu, Koichi

PY - 2016

Y1 - 2016

N2 - In the study of biological effects of ELF electric field, we found that the blood flow changes when the field is exposed to our body. The aggregability of red blood cells (RBC’s) in vivo increases right after the field exposure. To elucidate this phenomenon, an experimental study was conducted. Electric field was applied to the blood sample on a slide glass using insulated metal electrodes to make the current density 100 mA/m2 which simulates the current induced inside an adult body with a therapeutic instrument of electric field exposure. As a result, the ratio of the aggregated RBC’s increased about 25% in the field exposure. Through this study, the change in the RBC aggregability was confirmed in the well-controlled in vitro measurement. This suggests the possibility that the blood property change is caused not by the physiological change but by the physical change that is observable in the in vitro condition.

AB - In the study of biological effects of ELF electric field, we found that the blood flow changes when the field is exposed to our body. The aggregability of red blood cells (RBC’s) in vivo increases right after the field exposure. To elucidate this phenomenon, an experimental study was conducted. Electric field was applied to the blood sample on a slide glass using insulated metal electrodes to make the current density 100 mA/m2 which simulates the current induced inside an adult body with a therapeutic instrument of electric field exposure. As a result, the ratio of the aggregated RBC’s increased about 25% in the field exposure. Through this study, the change in the RBC aggregability was confirmed in the well-controlled in vitro measurement. This suggests the possibility that the blood property change is caused not by the physiological change but by the physical change that is observable in the in vitro condition.

KW - Aggregability

KW - Biological effects

KW - Blood flow

KW - ELF electric field

KW - Induced current

KW - Red blood cells (RBC’s)

UR - http://www.scopus.com/inward/record.url?scp=85009876972&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85009876972&partnerID=8YFLogxK

M3 - Article

VL - 54

SP - 1

EP - 2

JO - BME = Bio medical engineering / henshu, Nihon ME Gakkai

JF - BME = Bio medical engineering / henshu, Nihon ME Gakkai

SN - 1347-443X

IS - PROC

ER -