Gating of SEPs by contraction of the contralateral homologous muscle during the preparatory period of self-initiated plantar flexion

Toshiaki Wasaka, Hiroki Nakata, Tetsuo Kida, Ryusuke Kakigi

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

To investigate the centrifugal change in somatosensory information processing caused by contraction of the contralateral homologous muscle, we recorded the somatosensory-evoked potentials (SEPs) during the preparatory period of a self-initiated plantar flexion. The SEPs following stimulation of the right tibial nerve at the popliteal fossa were recorded in nine healthy subjects. Self-initiated plantar flexion of the left ankle was performed once every 5 to 7 s. The electrical stimulation was delivered continuously, and the subjects were instructed to concentrate on the movement and not to pay attention to the electrical stimulation. Based on the components of movement-related cortical potential, Bereitschaftspotential (BP) and Negative slope (NS), the preparatory period was divided into four sub-periods (NS, BP-1, BP-2, and Pre-BP). To obtain pre-movement SEPs, the signals following stimulation in each sub-period were averaged. SEPs were attenuated in the preparatory period, especially in the NS sub-period. The amplitude of N40 component was significantly attenuated compared with that in the stationary state and other sub-periods. The amplitude of P53 and N70 was smaller in the NS sub-period than other pre-movement sub-periods. Since there was no centripetal effect on SEPs in the preparatory period, these findings suggested that the activity of motor-related areas modulated the somatosensory information from the contralateral non-movement limb (centrifugal gating). It was assumed that an inhibition on the somatosensory inputs from contralateral limb was caused by the projection via either the corpus callosum or ipsilateral cortico-cortical projections.

Original languageEnglish
Pages (from-to)354-360
Number of pages7
JournalCognitive Brain Research
Volume23
Issue number2-3
DOIs
Publication statusPublished - 2005 May

Fingerprint

Somatosensory Evoked Potentials
Contingent Negative Variation
Muscles
Electric Stimulation
Extremities
Tibial Nerve
Corpus Callosum
Motor Cortex
Automatic Data Processing
Ankle
Healthy Volunteers

Keywords

  • Centrifugal gating
  • Homologous muscle
  • Negative slope
  • Self-initiated voluntary movement
  • SEPs

ASJC Scopus subject areas

  • Behavioral Neuroscience
  • Cognitive Neuroscience
  • Experimental and Cognitive Psychology

Cite this

Gating of SEPs by contraction of the contralateral homologous muscle during the preparatory period of self-initiated plantar flexion. / Wasaka, Toshiaki; Nakata, Hiroki; Kida, Tetsuo; Kakigi, Ryusuke.

In: Cognitive Brain Research, Vol. 23, No. 2-3, 05.2005, p. 354-360.

Research output: Contribution to journalArticle

Wasaka, Toshiaki ; Nakata, Hiroki ; Kida, Tetsuo ; Kakigi, Ryusuke. / Gating of SEPs by contraction of the contralateral homologous muscle during the preparatory period of self-initiated plantar flexion. In: Cognitive Brain Research. 2005 ; Vol. 23, No. 2-3. pp. 354-360.
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