GnIH and GnRH expressions in the central nervous system and pituitary of Indian major carp, Labeo rohita during ontogeny: An immunocytochemical study

Saikat Biswas, Arun G. Jadhao, Claudia Pinelli, Nikhil V. Palande, Kazuyoshi Tsutsui

    Research output: Contribution to journalArticle

    23 Citations (Scopus)

    Abstract

    Gonadotropin-releasing hormone (GnRH) is the major hypothalamic neuropeptide stimulating gonadotropin secretion in vertebrates. In 2000, gonadotropin-inhibitory hormone (GnIH) was discovered as a hypothalamic neuropeptide that inhibits gonadotropin secretion in birds. Subsequent studies have shown that GnIH is present in the brain of other vertebrates. We show for the first time GnIH immunoreactivity in the central nervous system and pituitary during development of Indian major carp, Labeo rohita and compare it with the localization of GnRH. GnIH and GnRH immunoreactivities were observed from the olfactory system to spinal cord throughout development. In the brain, both neuropeptides were localized in the telencephalon, diencephalon including the preoptic area and rhombencephalon. The localization of GnIH and GnRH in the pituitary suggests that these neuropeptides are involved in the regulation of pituitary hormones by an autocrine manner during development. In addition, the presence of GnIH and GnRH in several other brain regions including the olfactory system suggests their involvement in the regulation of other physiological functions.

    Original languageEnglish
    Pages (from-to)88-92
    Number of pages5
    JournalGeneral and Comparative Endocrinology
    Volume220
    DOIs
    Publication statusPublished - 2015 Sep 1

    Keywords

    • Carp
    • GnIH
    • GnRH
    • Ontogeny
    • Pituitary

    ASJC Scopus subject areas

    • Endocrinology

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