GnIH and GnRH expressions in the central nervous system and pituitary of Indian major carp, Labeo rohita during ontogeny

An immunocytochemical study

Saikat Biswas, Arun G. Jadhao, Claudia Pinelli, Nikhil V. Palande, Kazuyoshi Tsutsui

    Research output: Contribution to journalArticle

    19 Citations (Scopus)

    Abstract

    Gonadotropin-releasing hormone (GnRH) is the major hypothalamic neuropeptide stimulating gonadotropin secretion in vertebrates. In 2000, gonadotropin-inhibitory hormone (GnIH) was discovered as a hypothalamic neuropeptide that inhibits gonadotropin secretion in birds. Subsequent studies have shown that GnIH is present in the brain of other vertebrates. We show for the first time GnIH immunoreactivity in the central nervous system and pituitary during development of Indian major carp, Labeo rohita and compare it with the localization of GnRH. GnIH and GnRH immunoreactivities were observed from the olfactory system to spinal cord throughout development. In the brain, both neuropeptides were localized in the telencephalon, diencephalon including the preoptic area and rhombencephalon. The localization of GnIH and GnRH in the pituitary suggests that these neuropeptides are involved in the regulation of pituitary hormones by an autocrine manner during development. In addition, the presence of GnIH and GnRH in several other brain regions including the olfactory system suggests their involvement in the regulation of other physiological functions.

    Original languageEnglish
    Pages (from-to)88-92
    Number of pages5
    JournalGeneral and Comparative Endocrinology
    Volume220
    DOIs
    Publication statusPublished - 2015 Sep 1

    Fingerprint

    Labeo rohita
    Carps
    gonadotropin-releasing hormone
    gonadotropins
    Gonadotropins
    carp
    Gonadotropin-Releasing Hormone
    central nervous system
    ontogeny
    Central Nervous System
    hormones
    Hormones
    neuropeptides
    Neuropeptides
    brain
    Vertebrates
    Brain
    vertebrates
    secretion
    preoptic area

    Keywords

    • Carp
    • GnIH
    • GnRH
    • Ontogeny
    • Pituitary

    ASJC Scopus subject areas

    • Endocrinology

    Cite this

    GnIH and GnRH expressions in the central nervous system and pituitary of Indian major carp, Labeo rohita during ontogeny : An immunocytochemical study. / Biswas, Saikat; Jadhao, Arun G.; Pinelli, Claudia; Palande, Nikhil V.; Tsutsui, Kazuyoshi.

    In: General and Comparative Endocrinology, Vol. 220, 01.09.2015, p. 88-92.

    Research output: Contribution to journalArticle

    @article{1673aba091834273bf6f4026c00b69c8,
    title = "GnIH and GnRH expressions in the central nervous system and pituitary of Indian major carp, Labeo rohita during ontogeny: An immunocytochemical study",
    abstract = "Gonadotropin-releasing hormone (GnRH) is the major hypothalamic neuropeptide stimulating gonadotropin secretion in vertebrates. In 2000, gonadotropin-inhibitory hormone (GnIH) was discovered as a hypothalamic neuropeptide that inhibits gonadotropin secretion in birds. Subsequent studies have shown that GnIH is present in the brain of other vertebrates. We show for the first time GnIH immunoreactivity in the central nervous system and pituitary during development of Indian major carp, Labeo rohita and compare it with the localization of GnRH. GnIH and GnRH immunoreactivities were observed from the olfactory system to spinal cord throughout development. In the brain, both neuropeptides were localized in the telencephalon, diencephalon including the preoptic area and rhombencephalon. The localization of GnIH and GnRH in the pituitary suggests that these neuropeptides are involved in the regulation of pituitary hormones by an autocrine manner during development. In addition, the presence of GnIH and GnRH in several other brain regions including the olfactory system suggests their involvement in the regulation of other physiological functions.",
    keywords = "Carp, GnIH, GnRH, Ontogeny, Pituitary",
    author = "Saikat Biswas and Jadhao, {Arun G.} and Claudia Pinelli and Palande, {Nikhil V.} and Kazuyoshi Tsutsui",
    year = "2015",
    month = "9",
    day = "1",
    doi = "10.1016/j.ygcen.2014.06.005",
    language = "English",
    volume = "220",
    pages = "88--92",
    journal = "General and Comparative Endocrinology",
    issn = "0016-6480",
    publisher = "Academic Press Inc.",

    }

    TY - JOUR

    T1 - GnIH and GnRH expressions in the central nervous system and pituitary of Indian major carp, Labeo rohita during ontogeny

    T2 - An immunocytochemical study

    AU - Biswas, Saikat

    AU - Jadhao, Arun G.

    AU - Pinelli, Claudia

    AU - Palande, Nikhil V.

    AU - Tsutsui, Kazuyoshi

    PY - 2015/9/1

    Y1 - 2015/9/1

    N2 - Gonadotropin-releasing hormone (GnRH) is the major hypothalamic neuropeptide stimulating gonadotropin secretion in vertebrates. In 2000, gonadotropin-inhibitory hormone (GnIH) was discovered as a hypothalamic neuropeptide that inhibits gonadotropin secretion in birds. Subsequent studies have shown that GnIH is present in the brain of other vertebrates. We show for the first time GnIH immunoreactivity in the central nervous system and pituitary during development of Indian major carp, Labeo rohita and compare it with the localization of GnRH. GnIH and GnRH immunoreactivities were observed from the olfactory system to spinal cord throughout development. In the brain, both neuropeptides were localized in the telencephalon, diencephalon including the preoptic area and rhombencephalon. The localization of GnIH and GnRH in the pituitary suggests that these neuropeptides are involved in the regulation of pituitary hormones by an autocrine manner during development. In addition, the presence of GnIH and GnRH in several other brain regions including the olfactory system suggests their involvement in the regulation of other physiological functions.

    AB - Gonadotropin-releasing hormone (GnRH) is the major hypothalamic neuropeptide stimulating gonadotropin secretion in vertebrates. In 2000, gonadotropin-inhibitory hormone (GnIH) was discovered as a hypothalamic neuropeptide that inhibits gonadotropin secretion in birds. Subsequent studies have shown that GnIH is present in the brain of other vertebrates. We show for the first time GnIH immunoreactivity in the central nervous system and pituitary during development of Indian major carp, Labeo rohita and compare it with the localization of GnRH. GnIH and GnRH immunoreactivities were observed from the olfactory system to spinal cord throughout development. In the brain, both neuropeptides were localized in the telencephalon, diencephalon including the preoptic area and rhombencephalon. The localization of GnIH and GnRH in the pituitary suggests that these neuropeptides are involved in the regulation of pituitary hormones by an autocrine manner during development. In addition, the presence of GnIH and GnRH in several other brain regions including the olfactory system suggests their involvement in the regulation of other physiological functions.

    KW - Carp

    KW - GnIH

    KW - GnRH

    KW - Ontogeny

    KW - Pituitary

    UR - http://www.scopus.com/inward/record.url?scp=84941186176&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=84941186176&partnerID=8YFLogxK

    U2 - 10.1016/j.ygcen.2014.06.005

    DO - 10.1016/j.ygcen.2014.06.005

    M3 - Article

    VL - 220

    SP - 88

    EP - 92

    JO - General and Comparative Endocrinology

    JF - General and Comparative Endocrinology

    SN - 0016-6480

    ER -