Grafting poly(ethylene glycol) to a glass surface via a photocleavable linker for light-induced cell micropatterning and cell proliferation control

Yukiko Kikuchi, Jun Nakanishi, Hidekazu Nakayama, Takahiro Shimizu, Yutaro Yoshino, Kazuo Yamaguchi, Yasuhiko Yoshida, Yasuhiro Horiike

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

This paper describes a glass substrate having a photocleavable poly(ethylene glycol) (PEG) designed for light-induced cell micropatterning. The substrate changed from non-cell-adhesive to cell-adhesive by the photocleavage of PEG. Cellular patterns maintained for more than 17 days, and they were able to be changed to control cell migration and proliferation at multi- and single-cell levels by irradiating their adjacent regions during cell cultivation.

Original languageEnglish
Pages (from-to)1062-1063
Number of pages2
JournalChemistry Letters
Volume37
Issue number10
DOIs
Publication statusPublished - 2008 Dec 1
Externally publishedYes

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Cell proliferation
Polyethylene glycols
Glass
Adhesives
Substrates

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Grafting poly(ethylene glycol) to a glass surface via a photocleavable linker for light-induced cell micropatterning and cell proliferation control. / Kikuchi, Yukiko; Nakanishi, Jun; Nakayama, Hidekazu; Shimizu, Takahiro; Yoshino, Yutaro; Yamaguchi, Kazuo; Yoshida, Yasuhiko; Horiike, Yasuhiro.

In: Chemistry Letters, Vol. 37, No. 10, 01.12.2008, p. 1062-1063.

Research output: Contribution to journalArticle

Kikuchi, Yukiko ; Nakanishi, Jun ; Nakayama, Hidekazu ; Shimizu, Takahiro ; Yoshino, Yutaro ; Yamaguchi, Kazuo ; Yoshida, Yasuhiko ; Horiike, Yasuhiro. / Grafting poly(ethylene glycol) to a glass surface via a photocleavable linker for light-induced cell micropatterning and cell proliferation control. In: Chemistry Letters. 2008 ; Vol. 37, No. 10. pp. 1062-1063.
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