Helix-coil transition and 1/f fluctuation in a polypeptide

Mitsunori Takano, Takuya Takahashi, Kuniaki Nagayama

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

We report on molecular dynamics simulations of the helix-coil transition of a polypeptide. The simulated transition was two-state-like and similar to the solid-liquid-like transition that has been observed in computer simulations of an atomic cluster. At the transition temperature, the polypeptide chain fluctuated between a helical and a random-coil state, and we observed 1/f fluctuation through potential-energy fluctuations. The origin of the observed 1/f fluctuation is discussed, considering the underlying potential-energy landscape.

Original languageEnglish
Pages (from-to)5691-5694
Number of pages4
JournalPhysical Review Letters
Volume80
Issue number25
DOIs
Publication statusPublished - 1998

ASJC Scopus subject areas

  • Physics and Astronomy(all)

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