Hemocompatibility of DLC coating for blood analysis devices

K. Shiba, Y. Ohgoe, K. Hirakuri, Jun Mizuno, Shuichi Shoji, K. Ozeki, K. Sato, N. Fukata, A. Alanazi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

The studies of Diamond-Like carbon (DLC) coated medical devices have reported possibility for developing blood analysis devices. DLC film is a surface modification technique for biomaterials due to their hemocompatibility, low friction, and reasonableness. We have deposited DLC film on silicon (Si), cyclic olefin polymer (COP), polycarbonate (PC), SU-8 and polydimethylsiloxane (PDMS) by using r.f. plasma enhanced chemical vapor deposition (r.f.-PECVD) method. These materials have been used extensively in micro-channel devices. The hemocompatibility, chemical composition, structure, wettability, roughness, and surface morphology of the samples have been investigated by in-vitro test with sheep blood, X-ray photoelectron spectroscopy (XPS), Raman spectroscopy (Raman), a contact angle measurement, atomic force microscopy (AFM). The result indicated that the satisfied hemocompatibility was obtained for the DLC on COP and PDMS. Moreover, it was observed that hemocompatibility was influenced by surface conditions of sample DLC coating to COP and PDMS are expected as a surface modification technique for the micro-channel with hemocompatibility.

Original languageEnglish
Title of host publication2014 International Conference on Electronics Packaging, ICEP 2014
PublisherIEEE Computer Society
Pages748-751
Number of pages4
ISBN (Print)9784904090107
DOIs
Publication statusPublished - 2014
Event2014 International Conference on Electronics Packaging, ICEP 2014 - Toyama
Duration: 2014 Apr 232014 Apr 25

Other

Other2014 International Conference on Electronics Packaging, ICEP 2014
CityToyama
Period14/4/2314/4/25

Fingerprint

Cycloparaffins
Diamond
Polydimethylsiloxane
Olefins
Diamonds
Diamond like carbon films
Polymers
polycarbonate
Blood
Carbon
Coatings
Surface treatment
Biocompatible Materials
Silicon
Plasma enhanced chemical vapor deposition
Angle measurement
Polycarbonates
Biomaterials
Contact angle
Surface morphology

Keywords

  • blood analysis
  • diamond-like carbon (DLC)
  • hemocompatibility
  • micro channel
  • micro fluidic device

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials

Cite this

Shiba, K., Ohgoe, Y., Hirakuri, K., Mizuno, J., Shoji, S., Ozeki, K., ... Alanazi, A. (2014). Hemocompatibility of DLC coating for blood analysis devices. In 2014 International Conference on Electronics Packaging, ICEP 2014 (pp. 748-751). [6826781] IEEE Computer Society. https://doi.org/10.1109/ICEP.2014.6826781

Hemocompatibility of DLC coating for blood analysis devices. / Shiba, K.; Ohgoe, Y.; Hirakuri, K.; Mizuno, Jun; Shoji, Shuichi; Ozeki, K.; Sato, K.; Fukata, N.; Alanazi, A.

2014 International Conference on Electronics Packaging, ICEP 2014. IEEE Computer Society, 2014. p. 748-751 6826781.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Shiba, K, Ohgoe, Y, Hirakuri, K, Mizuno, J, Shoji, S, Ozeki, K, Sato, K, Fukata, N & Alanazi, A 2014, Hemocompatibility of DLC coating for blood analysis devices. in 2014 International Conference on Electronics Packaging, ICEP 2014., 6826781, IEEE Computer Society, pp. 748-751, 2014 International Conference on Electronics Packaging, ICEP 2014, Toyama, 14/4/23. https://doi.org/10.1109/ICEP.2014.6826781
Shiba K, Ohgoe Y, Hirakuri K, Mizuno J, Shoji S, Ozeki K et al. Hemocompatibility of DLC coating for blood analysis devices. In 2014 International Conference on Electronics Packaging, ICEP 2014. IEEE Computer Society. 2014. p. 748-751. 6826781 https://doi.org/10.1109/ICEP.2014.6826781
Shiba, K. ; Ohgoe, Y. ; Hirakuri, K. ; Mizuno, Jun ; Shoji, Shuichi ; Ozeki, K. ; Sato, K. ; Fukata, N. ; Alanazi, A. / Hemocompatibility of DLC coating for blood analysis devices. 2014 International Conference on Electronics Packaging, ICEP 2014. IEEE Computer Society, 2014. pp. 748-751
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AB - The studies of Diamond-Like carbon (DLC) coated medical devices have reported possibility for developing blood analysis devices. DLC film is a surface modification technique for biomaterials due to their hemocompatibility, low friction, and reasonableness. We have deposited DLC film on silicon (Si), cyclic olefin polymer (COP), polycarbonate (PC), SU-8 and polydimethylsiloxane (PDMS) by using r.f. plasma enhanced chemical vapor deposition (r.f.-PECVD) method. These materials have been used extensively in micro-channel devices. The hemocompatibility, chemical composition, structure, wettability, roughness, and surface morphology of the samples have been investigated by in-vitro test with sheep blood, X-ray photoelectron spectroscopy (XPS), Raman spectroscopy (Raman), a contact angle measurement, atomic force microscopy (AFM). The result indicated that the satisfied hemocompatibility was obtained for the DLC on COP and PDMS. Moreover, it was observed that hemocompatibility was influenced by surface conditions of sample DLC coating to COP and PDMS are expected as a surface modification technique for the micro-channel with hemocompatibility.

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