Hemocompatibility of DLC coating for blood analysis devices

K. Shiba, Y. Ohgoe, K. Hirakuri, J. Mizuno, S. Shoji, K. Ozeki, K. Sato, N. Fukata, A. Alanazi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

The studies of Diamond-Like carbon (DLC) coated medical devices have reported possibility for developing blood analysis devices. DLC film is a surface modification technique for biomaterials due to their hemocompatibility, low friction, and reasonableness. We have deposited DLC film on silicon (Si), cyclic olefin polymer (COP), polycarbonate (PC), SU-8 and polydimethylsiloxane (PDMS) by using r.f. plasma enhanced chemical vapor deposition (r.f.-PECVD) method. These materials have been used extensively in micro-channel devices. The hemocompatibility, chemical composition, structure, wettability, roughness, and surface morphology of the samples have been investigated by in-vitro test with sheep blood, X-ray photoelectron spectroscopy (XPS), Raman spectroscopy (Raman), a contact angle measurement, atomic force microscopy (AFM). The result indicated that the satisfied hemocompatibility was obtained for the DLC on COP and PDMS. Moreover, it was observed that hemocompatibility was influenced by surface conditions of sample DLC coating to COP and PDMS are expected as a surface modification technique for the micro-channel with hemocompatibility.

Original languageEnglish
Title of host publication2014 International Conference on Electronics Packaging, ICEP 2014
PublisherIEEE Computer Society
Pages748-751
Number of pages4
ISBN (Print)9784904090107
DOIs
Publication statusPublished - 2014 Jan 1
Event2014 International Conference on Electronics Packaging, ICEP 2014 - Toyama, Japan
Duration: 2014 Apr 232014 Apr 25

Publication series

Name2014 International Conference on Electronics Packaging, ICEP 2014

Conference

Conference2014 International Conference on Electronics Packaging, ICEP 2014
CountryJapan
CityToyama
Period14/4/2314/4/25

Keywords

  • blood analysis
  • diamond-like carbon (DLC)
  • hemocompatibility
  • micro channel
  • micro fluidic device

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials

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  • Cite this

    Shiba, K., Ohgoe, Y., Hirakuri, K., Mizuno, J., Shoji, S., Ozeki, K., Sato, K., Fukata, N., & Alanazi, A. (2014). Hemocompatibility of DLC coating for blood analysis devices. In 2014 International Conference on Electronics Packaging, ICEP 2014 (pp. 748-751). [6826781] (2014 International Conference on Electronics Packaging, ICEP 2014). IEEE Computer Society. https://doi.org/10.1109/ICEP.2014.6826781