Hepatoprotective effect of a hot-water extract from the edible thorny oyster Spondylus varius on carbon tetrachloride-induced liver injury in mice

Tomoyuki Koyama, Ritsu Chounan, Daisuke Uemura, Kohji Yamaguchi, Kazunaga Yazawa

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

The edible thorny oyster, Spondylus varius (Mizuirishoujou), was found to suppress the carbon tetrachloride-induced increase in serum aspartate and alanine aminotransferase activities in mice. Significant suppressive effects on these enzyme activities were found in the fraction eluted with 75% ethanol from polystyrene gel in a dose-dependent manner. These results suggest that S. varius exerts a protective effect against liver injury.

Original languageEnglish
Pages (from-to)729-731
Number of pages3
JournalBioscience, Biotechnology and Biochemistry
Volume70
Issue number3
DOIs
Publication statusPublished - 2006
Externally publishedYes

Fingerprint

Ostreidae
hepatoprotective effect
carbon tetrachloride
Carbon tetrachloride
Carbon Tetrachloride
Polystyrenes
polystyrenes
Enzyme activity
Aspartate Aminotransferases
Alanine Transaminase
alanine transaminase
aspartate transaminase
Liver
oysters
Ethanol
Gels
ethanol
gels
enzyme activity
liver

Keywords

  • Carbon tetrachloride
  • Functional food
  • Hepatoprotective effect
  • Spondylus varius
  • Thorny oyster

ASJC Scopus subject areas

  • Bioengineering
  • Biotechnology
  • Biochemistry
  • Biochemistry, Genetics and Molecular Biology(all)
  • Chemistry (miscellaneous)
  • Applied Microbiology and Biotechnology
  • Food Science

Cite this

Hepatoprotective effect of a hot-water extract from the edible thorny oyster Spondylus varius on carbon tetrachloride-induced liver injury in mice. / Koyama, Tomoyuki; Chounan, Ritsu; Uemura, Daisuke; Yamaguchi, Kohji; Yazawa, Kazunaga.

In: Bioscience, Biotechnology and Biochemistry, Vol. 70, No. 3, 2006, p. 729-731.

Research output: Contribution to journalArticle

Koyama, Tomoyuki ; Chounan, Ritsu ; Uemura, Daisuke ; Yamaguchi, Kohji ; Yazawa, Kazunaga. / Hepatoprotective effect of a hot-water extract from the edible thorny oyster Spondylus varius on carbon tetrachloride-induced liver injury in mice. In: Bioscience, Biotechnology and Biochemistry. 2006 ; Vol. 70, No. 3. pp. 729-731.
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