Hierarchical multi-label classification incorporating prior information for gene function prediction

Benhui Chen; Jinglu Hu

doi:10.1109/ISDA.2010.5687261

Hierarchical multi-label classification incorporating prior information for gene function prediction

Benhui Chen^*, Jinglu Hu

^*Corresponding author for this work

Graduate School of Information, Production and Systems

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

3 Citations (Scopus)

Abstract

This paper proposes an improved Hierarchical Multi-label Classification (HMC) method for solving the gene function prediction. The HMC task is transferred into a series of binary SVM classification tasks. By introducing the hierarchy constraint into learning procedures, two measures with incorporating prior information are implemented to improve the HMC performance. Firstly, for imbalanced functional classes, a hierarchical SMOTE is proposed as over-sampling preprocessing to improve the SVM learning performance. Secondly, an improved True Path Rule consistency approach is introduced to ensemble the results of binary probabilistic SVM classifications. It can improve the classification results and guarantee the hierarchy constraint of classes.

Original language	English
Title of host publication	Proceedings of the 2010 10th International Conference on Intelligent Systems Design and Applications, ISDA'10
Pages	231-236
Number of pages	6
DOIs	https://doi.org/10.1109/ISDA.2010.5687261
Publication status	Published - 2010 Dec 1
Event	2010 10th International Conference on Intelligent Systems Design and Applications, ISDA'10 - Cairo, Egypt Duration: 2010 Nov 29 → 2010 Dec 1

Publication series

Name	Proceedings of the 2010 10th International Conference on Intelligent Systems Design and Applications, ISDA'10

Conference

Conference	2010 10th International Conference on Intelligent Systems Design and Applications, ISDA'10
Country/Territory	Egypt
City	Cairo
Period	10/11/29 → 10/12/1

Keywords

Consistency ensemble
Gene function prediction
Hierarchical SMOTE
Hierarchical multi-label classification

ASJC Scopus subject areas

Artificial Intelligence
Computer Science Applications
Hardware and Architecture

Access to Document

10.1109/ISDA.2010.5687261

Cite this

Chen, B., & Hu, J. (2010). Hierarchical multi-label classification incorporating prior information for gene function prediction. In Proceedings of the 2010 10th International Conference on Intelligent Systems Design and Applications, ISDA'10 (pp. 231-236). [5687261] (Proceedings of the 2010 10th International Conference on Intelligent Systems Design and Applications, ISDA'10). https://doi.org/10.1109/ISDA.2010.5687261

Hierarchical multi-label classification incorporating prior information for gene function prediction. / Chen, Benhui; Hu, Jinglu.

Proceedings of the 2010 10th International Conference on Intelligent Systems Design and Applications, ISDA'10. 2010. p. 231-236 5687261 (Proceedings of the 2010 10th International Conference on Intelligent Systems Design and Applications, ISDA'10).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Chen, B & Hu, J 2010, Hierarchical multi-label classification incorporating prior information for gene function prediction. in Proceedings of the 2010 10th International Conference on Intelligent Systems Design and Applications, ISDA'10., 5687261, Proceedings of the 2010 10th International Conference on Intelligent Systems Design and Applications, ISDA'10, pp. 231-236, 2010 10th International Conference on Intelligent Systems Design and Applications, ISDA'10, Cairo, Egypt, 10/11/29. https://doi.org/10.1109/ISDA.2010.5687261

Chen B, Hu J. Hierarchical multi-label classification incorporating prior information for gene function prediction. In Proceedings of the 2010 10th International Conference on Intelligent Systems Design and Applications, ISDA'10. 2010. p. 231-236. 5687261. (Proceedings of the 2010 10th International Conference on Intelligent Systems Design and Applications, ISDA'10). doi: 10.1109/ISDA.2010.5687261

Chen, Benhui ; Hu, Jinglu. / Hierarchical multi-label classification incorporating prior information for gene function prediction. Proceedings of the 2010 10th International Conference on Intelligent Systems Design and Applications, ISDA'10. 2010. pp. 231-236 (Proceedings of the 2010 10th International Conference on Intelligent Systems Design and Applications, ISDA'10).

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Hierarchical multi-label classification incorporating prior information for gene function prediction

Abstract

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Keywords

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