High-pressure stopped-flow nuclear magnetic resonance apparatus for the study of fast reactions in solution

Shigenobu Funahashi; Koji Ishihara; Sen Ichi Aizawa; Takashi Sugata; Masao Ishii; Yasuhiro Inada; Motoharu Tanaka

doi:10.1063/1.1144426

High-pressure stopped-flow nuclear magnetic resonance apparatus for the study of fast reactions in solution

Shigenobu Funahashi^*, Koji Ishihara, Sen Ichi Aizawa, Takashi Sugata, Masao Ishii, Yasuhiro Inada, Motoharu Tanaka

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

A high-pressure proton nuclear magnetic resonance (NMR) probe for a stopped-flow method has been developed, which enables us to follow fast reactions at various pressures up to 200 MPa. The high-pressure stopped-flow NMR (HP-SF-NMR) method has been applied to the study of several reactions at high pressures: the reaction of tetramethyltin with iodine in chloroform and the solvent exchange reaction on aluminum(III) ion in N, N-dimethylformamide. The volumes of activation for the iodomerization of tin and the solvent exchange reaction on aluminum(III) were determined to be -24.9±3.8 cm³ mol^-1 and -2.2±0.8 cm³ mol^-1, respectively. The apparatus permits measurement of activation volumes for reactions with half lives longer than a few seconds if the nuclear relaxation time of the measured proton is short enough. Several requirements for the applicability of HP-SF-NMR are discussed.

Original language	English
Pages (from-to)	130-134
Number of pages	5
Journal	Review of Scientific Instruments
Volume	64
Issue number	1
DOIs	https://doi.org/10.1063/1.1144426
Publication status	Published - 1993
Externally published	Yes

ASJC Scopus subject areas

Instrumentation

Access to Document

10.1063/1.1144426

Cite this

@article{d976ae4f12bb4620930ea83df2631e2c,

title = "High-pressure stopped-flow nuclear magnetic resonance apparatus for the study of fast reactions in solution",

abstract = "A high-pressure proton nuclear magnetic resonance (NMR) probe for a stopped-flow method has been developed, which enables us to follow fast reactions at various pressures up to 200 MPa. The high-pressure stopped-flow NMR (HP-SF-NMR) method has been applied to the study of several reactions at high pressures: the reaction of tetramethyltin with iodine in chloroform and the solvent exchange reaction on aluminum(III) ion in N, N-dimethylformamide. The volumes of activation for the iodomerization of tin and the solvent exchange reaction on aluminum(III) were determined to be -24.9±3.8 cm3 mol-1 and -2.2±0.8 cm3 mol-1, respectively. The apparatus permits measurement of activation volumes for reactions with half lives longer than a few seconds if the nuclear relaxation time of the measured proton is short enough. Several requirements for the applicability of HP-SF-NMR are discussed.",

author = "Shigenobu Funahashi and Koji Ishihara and Aizawa, {Sen Ichi} and Takashi Sugata and Masao Ishii and Yasuhiro Inada and Motoharu Tanaka",

year = "1993",

doi = "10.1063/1.1144426",

language = "English",

volume = "64",

pages = "130--134",

journal = "Review of Scientific Instruments",

issn = "0034-6748",

publisher = "American Institute of Physics Publising LLC",

number = "1",

}

TY - JOUR

T1 - High-pressure stopped-flow nuclear magnetic resonance apparatus for the study of fast reactions in solution

AU - Funahashi, Shigenobu

AU - Ishihara, Koji

AU - Aizawa, Sen Ichi

AU - Sugata, Takashi

AU - Ishii, Masao

AU - Inada, Yasuhiro

AU - Tanaka, Motoharu

PY - 1993

Y1 - 1993

N2 - A high-pressure proton nuclear magnetic resonance (NMR) probe for a stopped-flow method has been developed, which enables us to follow fast reactions at various pressures up to 200 MPa. The high-pressure stopped-flow NMR (HP-SF-NMR) method has been applied to the study of several reactions at high pressures: the reaction of tetramethyltin with iodine in chloroform and the solvent exchange reaction on aluminum(III) ion in N, N-dimethylformamide. The volumes of activation for the iodomerization of tin and the solvent exchange reaction on aluminum(III) were determined to be -24.9±3.8 cm3 mol-1 and -2.2±0.8 cm3 mol-1, respectively. The apparatus permits measurement of activation volumes for reactions with half lives longer than a few seconds if the nuclear relaxation time of the measured proton is short enough. Several requirements for the applicability of HP-SF-NMR are discussed.

AB - A high-pressure proton nuclear magnetic resonance (NMR) probe for a stopped-flow method has been developed, which enables us to follow fast reactions at various pressures up to 200 MPa. The high-pressure stopped-flow NMR (HP-SF-NMR) method has been applied to the study of several reactions at high pressures: the reaction of tetramethyltin with iodine in chloroform and the solvent exchange reaction on aluminum(III) ion in N, N-dimethylformamide. The volumes of activation for the iodomerization of tin and the solvent exchange reaction on aluminum(III) were determined to be -24.9±3.8 cm3 mol-1 and -2.2±0.8 cm3 mol-1, respectively. The apparatus permits measurement of activation volumes for reactions with half lives longer than a few seconds if the nuclear relaxation time of the measured proton is short enough. Several requirements for the applicability of HP-SF-NMR are discussed.

UR - http://www.scopus.com/inward/record.url?scp=0000393076&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0000393076&partnerID=8YFLogxK

U2 - 10.1063/1.1144426

DO - 10.1063/1.1144426

M3 - Article

AN - SCOPUS:0000393076

SN - 0034-6748

VL - 64

SP - 130

EP - 134

JO - Review of Scientific Instruments

JF - Review of Scientific Instruments

IS - 1

ER -

High-pressure stopped-flow nuclear magnetic resonance apparatus for the study of fast reactions in solution

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this