High-pressure stopped-flow nuclear magnetic resonance apparatus for the study of fast reactions in solution

Shigenobu Funahashi; Koji Ishihara; Sen Ichi Aizawa; Takashi Sugata; Masao Ishii; Yasuhiro Inada; Motoharu Tanaka

doi:10.1063/1.1144426

High-pressure stopped-flow nuclear magnetic resonance apparatus for the study of fast reactions in solution

Shigenobu Funahashi^*, Koji Ishihara, Sen Ichi Aizawa, Takashi Sugata, Masao Ishii, Yasuhiro Inada, Motoharu Tanaka

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

A high-pressure proton nuclear magnetic resonance (NMR) probe for a stopped-flow method has been developed, which enables us to follow fast reactions at various pressures up to 200 MPa. The high-pressure stopped-flow NMR (HP-SF-NMR) method has been applied to the study of several reactions at high pressures: the reaction of tetramethyltin with iodine in chloroform and the solvent exchange reaction on aluminum(III) ion in N, N-dimethylformamide. The volumes of activation for the iodomerization of tin and the solvent exchange reaction on aluminum(III) were determined to be -24.9±3.8 cm³ mol^-1 and -2.2±0.8 cm³ mol^-1, respectively. The apparatus permits measurement of activation volumes for reactions with half lives longer than a few seconds if the nuclear relaxation time of the measured proton is short enough. Several requirements for the applicability of HP-SF-NMR are discussed.

Original language	English
Pages (from-to)	130-134
Number of pages	5
Journal	Review of Scientific Instruments
Volume	64
Issue number	1
DOIs	https://doi.org/10.1063/1.1144426
Publication status	Published - 1993
Externally published	Yes

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Instrumentation

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High-pressure stopped-flow nuclear magnetic resonance apparatus for the study of fast reactions in solution. / Funahashi, Shigenobu; Ishihara, Koji; Aizawa, Sen Ichi; Sugata, Takashi; Ishii, Masao; Inada, Yasuhiro; Tanaka, Motoharu.

In: Review of Scientific Instruments, Vol. 64, No. 1, 1993, p. 130-134.

Research output: Contribution to journal › Article › peer-review

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AU - Ishii, Masao

AU - Inada, Yasuhiro

AU - Tanaka, Motoharu

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High-pressure stopped-flow nuclear magnetic resonance apparatus for the study of fast reactions in solution

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