High resolution phoswich gamma-ray imager utilizing monolithic MPPC arrays with submillimeter pixelized crystals

T. Kato, Jun Kataoka, T. Nakamori, A. Kishimoto, S. Yamamoto, K. Sato, Y. Ishikawa, K. Yamamura, N. Kawabata, H. Ikeda, K. Kamada

    Research output: Contribution to journalArticle

    5 Citations (Scopus)

    Abstract

    We report the development of a high spatial resolution tweezers-type coincidence gamma-ray camera for medical imaging. This application consists of large-area monolithic Multi-Pixel Photon Counters (MPPCs) and submillimeter pixelized scintillator matrices. The MPPC array has 4 × 4 channels with a three-side buttable, very compact package. For typical operational gain of 7.5 × 105 at + 20 °C, gain fluctuation over the entire MPPC device is only ± 5.6%, and dark count rates (as measured at the 1 p.e. level) amount to 400 kcps per channel. We selected Ce-doped (Lu,Y) 2(SiO4)O (Ce:LYSO) and a brand-new scintillator, Ce-doped Gd3Al2Ga3O12 (Ce:GAGG) due to their high light yield and density. To improve the spatial resolution, these scintillators were fabricated into 15 × 15 matrices of 0.5 × 0.5 mm2 pixels. The Ce:LYSO and Ce:GAGG scintillator matrices were assembled into phosphor sandwich (phoswich) detectors, and then coupled to the MPPC array along with an acrylic light guide measuring 1 mm thick, and with summing operational amplifiers that compile the signals into four position-encoded analog outputs being used for signal readout. Spatial resolution of 1.1 mm was achieved with the coincidence imaging system using a 22Na point source. These results suggest that the gamma-ray imagers offer excellent potential for applications in high spatial medical imaging.

    Original languageEnglish
    Article numberP05022
    JournalJournal of Instrumentation
    Volume8
    Issue number5
    DOIs
    Publication statusPublished - 2013 May

    Fingerprint

    Phosphor
    Sandwich
    Gamma Rays
    Imager
    Scintillator
    Image sensors
    Gamma rays
    Phosphors
    phosphors
    Photon
    counters
    Crystal
    High Resolution
    Photons
    Pixel
    Pixels
    pixels
    scintillation counters
    gamma rays
    Crystals

    Keywords

    • Gamma camera, SPECT, PET PET/CT, coronary CT angiography (CTA)
    • Intra-operative probes
    • Photon detectors for UV, visible and IR photons (solid-state) (PIN diodes, APDs, Si-PMTs, G-APDs, CCDs, EBCCDs, EMCCDs etc)

    ASJC Scopus subject areas

    • Instrumentation
    • Mathematical Physics

    Cite this

    High resolution phoswich gamma-ray imager utilizing monolithic MPPC arrays with submillimeter pixelized crystals. / Kato, T.; Kataoka, Jun; Nakamori, T.; Kishimoto, A.; Yamamoto, S.; Sato, K.; Ishikawa, Y.; Yamamura, K.; Kawabata, N.; Ikeda, H.; Kamada, K.

    In: Journal of Instrumentation, Vol. 8, No. 5, P05022, 05.2013.

    Research output: Contribution to journalArticle

    Kato, T, Kataoka, J, Nakamori, T, Kishimoto, A, Yamamoto, S, Sato, K, Ishikawa, Y, Yamamura, K, Kawabata, N, Ikeda, H & Kamada, K 2013, 'High resolution phoswich gamma-ray imager utilizing monolithic MPPC arrays with submillimeter pixelized crystals', Journal of Instrumentation, vol. 8, no. 5, P05022. https://doi.org/10.1088/1748-0221/8/05/P05022
    Kato, T. ; Kataoka, Jun ; Nakamori, T. ; Kishimoto, A. ; Yamamoto, S. ; Sato, K. ; Ishikawa, Y. ; Yamamura, K. ; Kawabata, N. ; Ikeda, H. ; Kamada, K. / High resolution phoswich gamma-ray imager utilizing monolithic MPPC arrays with submillimeter pixelized crystals. In: Journal of Instrumentation. 2013 ; Vol. 8, No. 5.
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    AU - Kataoka, Jun

    AU - Nakamori, T.

    AU - Kishimoto, A.

    AU - Yamamoto, S.

    AU - Sato, K.

    AU - Ishikawa, Y.

    AU - Yamamura, K.

    AU - Kawabata, N.

    AU - Ikeda, H.

    AU - Kamada, K.

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    AB - We report the development of a high spatial resolution tweezers-type coincidence gamma-ray camera for medical imaging. This application consists of large-area monolithic Multi-Pixel Photon Counters (MPPCs) and submillimeter pixelized scintillator matrices. The MPPC array has 4 × 4 channels with a three-side buttable, very compact package. For typical operational gain of 7.5 × 105 at + 20 °C, gain fluctuation over the entire MPPC device is only ± 5.6%, and dark count rates (as measured at the 1 p.e. level) amount to 400 kcps per channel. We selected Ce-doped (Lu,Y) 2(SiO4)O (Ce:LYSO) and a brand-new scintillator, Ce-doped Gd3Al2Ga3O12 (Ce:GAGG) due to their high light yield and density. To improve the spatial resolution, these scintillators were fabricated into 15 × 15 matrices of 0.5 × 0.5 mm2 pixels. The Ce:LYSO and Ce:GAGG scintillator matrices were assembled into phosphor sandwich (phoswich) detectors, and then coupled to the MPPC array along with an acrylic light guide measuring 1 mm thick, and with summing operational amplifiers that compile the signals into four position-encoded analog outputs being used for signal readout. Spatial resolution of 1.1 mm was achieved with the coincidence imaging system using a 22Na point source. These results suggest that the gamma-ray imagers offer excellent potential for applications in high spatial medical imaging.

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    KW - Photon detectors for UV, visible and IR photons (solid-state) (PIN diodes, APDs, Si-PMTs, G-APDs, CCDs, EBCCDs, EMCCDs etc)

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