High speed particles and biomolecules sorting microsystem using thermosensitive hydrogel and water two-phase flow

Takahiro Arakawa, Toshimitsu Izumi, Wataru Teragauchi, Tokihiko Aoki, Yoshitaka Shirasaki, Hirokazu Sugino, Takashi Funatsu, Shuichi Shoji

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

High speed particles and biomolecules sorter was realized using thermosensitive hydrogel and water two-phase sheath flow system. The two phase sheath flow consists of a water flow including samples and two hydrogel carrier flows is utilized instead of the air and water droplet two-phase flow used in the conventional commercialized cell sorter. Flow switching is performed by the sol-gel transfer of the thermosensitive hydrogel generated by the focused IR laser irradiation. High speed sorting less than 5.0 msec and no error sorting (3000 counts) was realized. Since sorting performed in simple PDMS-glass microchannels without any electric stimulation, the proposed system is suitable for bio-applications.

Original languageEnglish
Title of host publicationProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Pages58-61
Number of pages4
Volume2006
Publication statusPublished - 2006
Externally publishedYes
Event19th IEEE International Conference on Micro Electro Mechanical Systems - Istanbul
Duration: 2006 Jan 222006 Jan 26

Other

Other19th IEEE International Conference on Micro Electro Mechanical Systems
CityIstanbul
Period06/1/2206/1/26

Fingerprint

Microsystems
Biomolecules
Sorting
Hydrogels
Two phase flow
Particles (particulate matter)
Water
Laser beam effects
Microchannels
Sol-gels
Glass
Air

ASJC Scopus subject areas

  • Mechanical Engineering
  • Electrical and Electronic Engineering
  • Control and Systems Engineering

Cite this

Arakawa, T., Izumi, T., Teragauchi, W., Aoki, T., Shirasaki, Y., Sugino, H., ... Shoji, S. (2006). High speed particles and biomolecules sorting microsystem using thermosensitive hydrogel and water two-phase flow. In Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) (Vol. 2006, pp. 58-61). [1627735]

High speed particles and biomolecules sorting microsystem using thermosensitive hydrogel and water two-phase flow. / Arakawa, Takahiro; Izumi, Toshimitsu; Teragauchi, Wataru; Aoki, Tokihiko; Shirasaki, Yoshitaka; Sugino, Hirokazu; Funatsu, Takashi; Shoji, Shuichi.

Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). Vol. 2006 2006. p. 58-61 1627735.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Arakawa, T, Izumi, T, Teragauchi, W, Aoki, T, Shirasaki, Y, Sugino, H, Funatsu, T & Shoji, S 2006, High speed particles and biomolecules sorting microsystem using thermosensitive hydrogel and water two-phase flow. in Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). vol. 2006, 1627735, pp. 58-61, 19th IEEE International Conference on Micro Electro Mechanical Systems, Istanbul, 06/1/22.
Arakawa T, Izumi T, Teragauchi W, Aoki T, Shirasaki Y, Sugino H et al. High speed particles and biomolecules sorting microsystem using thermosensitive hydrogel and water two-phase flow. In Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). Vol. 2006. 2006. p. 58-61. 1627735
Arakawa, Takahiro ; Izumi, Toshimitsu ; Teragauchi, Wataru ; Aoki, Tokihiko ; Shirasaki, Yoshitaka ; Sugino, Hirokazu ; Funatsu, Takashi ; Shoji, Shuichi. / High speed particles and biomolecules sorting microsystem using thermosensitive hydrogel and water two-phase flow. Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). Vol. 2006 2006. pp. 58-61
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