Highly diastereo- and enantioselective construction of both central and axial chiralities by Rh-catalyzed [2 + 2 + 2] cycloaddition

Takanori Shibata, Mayumi Otomo, Yu Ki Tahara, Kohei Endo

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    23 Citations (Scopus)

    Abstract

    The cationic Rh-SEGPHOS complex catalyzed an intermolecular [2 + 2 + 2] cycloaddition of enynes, possessing an ortho-substituted aryl group on their alkyne terminus, with acetylenedicarboxylates. Bicyclic cyclohexa-1,3-dienes with both central and axial chiralities were obtained in extremely highly diastereo- and enantioselective manner.

    Original languageEnglish
    Pages (from-to)4296-4298
    Number of pages3
    JournalOrganic and Biomolecular Chemistry
    Volume6
    Issue number23
    DOIs
    Publication statusPublished - 2008

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    ASJC Scopus subject areas

    • Physical and Theoretical Chemistry
    • Organic Chemistry
    • Biochemistry

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