Highly diastereo- and enantioselective construction of both central and axial chiralities by Rh-catalyzed [2 + 2 + 2] cycloaddition

Takanori Shibata, Mayumi Otomo, Yu Ki Tahara, Kohei Endo

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

The cationic Rh-SEGPHOS complex catalyzed an intermolecular [2 + 2 + 2] cycloaddition of enynes, possessing an ortho-substituted aryl group on their alkyne terminus, with acetylenedicarboxylates. Bicyclic cyclohexa-1,3-dienes with both central and axial chiralities were obtained in extremely highly diastereo- and enantioselective manner.

Original languageEnglish
Pages (from-to)4296-4298
Number of pages3
JournalOrganic and Biomolecular Chemistry
Volume6
Issue number23
DOIs
Publication statusPublished - 2008 Nov 24

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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