Abstract
The enantioselective preparation of the tricyclo[4.4.0.05,7]dec-2-ene derivatives via the catalytic asymmetric intramolecular cyclopropanation (CAIMCP) reactions of α-diazo-β-keto esters with excellent ee (95-98% ee) is described. The chiral building blocks reported herein would be versatile intermediates for enantioselective natural products synthesis.
Original language | English |
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Pages (from-to) | 4855-4859 |
Number of pages | 5 |
Journal | Tetrahedron Letters |
Volume | 48 |
Issue number | 28 |
DOIs | |
Publication status | Published - 2007 Jul 9 |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry