Hormonal control of in vitro vitellogenin synthesis in Rana esculenta liver: Effects of mammalian and amphibian growth hormone

Oliana Carnevali, Gilberto Mosgoni, Kazutoshi Yamamoto, Tetsuya Kobayashi, Sakae Kikuyama, Alberta M. Polzonetti-Magni

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Estradiol 17-β is known to induce hepatic synthesis and secretion of vitellogenin in all species studied and in Rana esculenta, previous experiments demonstrated the involvement of pituitary in these processes; indeed, in addition to estradiol 17-β, homologous pituitary homogenate directly stimulated male and female liver to produce vitellogenin in tissue cultures. Therefore, the effect of ovine growth hormone (o-GH) and Rana catesbeiana growth hormone (f-GH) on hepatic vitellogenin synthesis was investigated. In the present in vitro experiments, both o-GH and f-GH positively stimulated vitellogenin synthesis, in female and male liver, in a dose-related fashion. No significant differences were found in VTG levels induced by o-GH and f-GH. The GH stimulatory effects, found during the different phases of the reproductive cycle, displayed different trends related to season and sex.

Original languageEnglish
Pages (from-to)406-414
Number of pages9
JournalGeneral and Comparative Endocrinology
Volume88
Issue number3
DOIs
Publication statusPublished - 1992
Externally publishedYes

ASJC Scopus subject areas

  • Endocrinology

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