How to ensure safety factors in the development of artificial heart: Verified by the usage of "modeling and simulation" technology

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

The author has involved in two types of clinically available artificial hearts in Japan for these 30 years. Firstly, Toyobo auxiliary pulsatile ventricular assist pump was commercialized in 1991 and over 700 clinical cases are reported in Japanese market. Secondly, an implantable non-pulsatile ventricular assist pump (EVAHEART, Sunmedical Tech. Res. Co.) has been implanted into 11 patients in Japan. The author has been establishing a methodology to eliminate considerable risk factors through a development of hydrodynamic performance test, durability test and biocompatibility test. These in vitro tests are all effective to ensure a safety of the system and also in vitro tests have a contribution to reduce a number of animal experiments.

Original languageEnglish
Title of host publicationLife System Modeling and Simulation - International Conference, LSMS 2007, Proceedings
Pages88-96
Number of pages9
Publication statusPublished - 2007 Dec 1
Event2007 International Conference on Life System Modeling and Simulation, LSMS 2007 - Shanghai, China
Duration: 2007 Sep 142007 Sep 17

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume4689 LNBI
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference2007 International Conference on Life System Modeling and Simulation, LSMS 2007
CountryChina
CityShanghai
Period07/9/1407/9/17

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

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  • Cite this

    Umezu, M. (2007). How to ensure safety factors in the development of artificial heart: Verified by the usage of "modeling and simulation" technology. In Life System Modeling and Simulation - International Conference, LSMS 2007, Proceedings (pp. 88-96). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 4689 LNBI).