How to ensure safety factors in the development of artificial heart

Verified by the usage of "modeling and simulation" technology

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    1 Citation (Scopus)

    Abstract

    The author has involved in two types of clinically available artificial hearts in Japan for these 30 years. Firstly, Toyobo auxiliary pulsatile ventricular assist pump was commercialized in 1991 and over 700 clinical cases are reported in Japanese market. Secondly, an implantable non-pulsatile ventricular assist pump (EVAHEART, Sunmedical Tech. Res. Co.) has been implanted into 11 patients in Japan. The author has been establishing a methodology to eliminate considerable risk factors through a development of hydrodynamic performance test, durability test and biocompatibility test. These in vitro tests are all effective to ensure a safety of the system and also in vitro tests have a contribution to reduce a number of animal experiments.

    Original languageEnglish
    Title of host publicationLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
    Pages88-96
    Number of pages9
    Volume4689 LNBI
    Publication statusPublished - 2007
    Event2007 International Conference on Life System Modeling and Simulation, LSMS 2007 - Shanghai
    Duration: 2007 Sep 142007 Sep 17

    Publication series

    NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
    Volume4689 LNBI
    ISSN (Print)03029743
    ISSN (Electronic)16113349

    Other

    Other2007 International Conference on Life System Modeling and Simulation, LSMS 2007
    CityShanghai
    Period07/9/1407/9/17

    Fingerprint

    Artificial heart
    Artificial Heart
    Safety factor
    Modeling and Simulation
    Japan
    Safety
    Pumps
    Technology
    Hydrodynamics
    Biocompatibility
    Pump
    Animals
    Durability
    Performance Test
    Risk Factors
    Eliminate
    Experiments
    Heart
    In Vitro Techniques
    Methodology

    ASJC Scopus subject areas

    • Computer Science(all)
    • Biochemistry, Genetics and Molecular Biology(all)
    • Theoretical Computer Science

    Cite this

    Umezu, M. (2007). How to ensure safety factors in the development of artificial heart: Verified by the usage of "modeling and simulation" technology. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 4689 LNBI, pp. 88-96). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 4689 LNBI).

    How to ensure safety factors in the development of artificial heart : Verified by the usage of "modeling and simulation" technology. / Umezu, Mitsuo.

    Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Vol. 4689 LNBI 2007. p. 88-96 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 4689 LNBI).

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Umezu, M 2007, How to ensure safety factors in the development of artificial heart: Verified by the usage of "modeling and simulation" technology. in Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). vol. 4689 LNBI, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), vol. 4689 LNBI, pp. 88-96, 2007 International Conference on Life System Modeling and Simulation, LSMS 2007, Shanghai, 07/9/14.
    Umezu M. How to ensure safety factors in the development of artificial heart: Verified by the usage of "modeling and simulation" technology. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Vol. 4689 LNBI. 2007. p. 88-96. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)).
    Umezu, Mitsuo. / How to ensure safety factors in the development of artificial heart : Verified by the usage of "modeling and simulation" technology. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Vol. 4689 LNBI 2007. pp. 88-96 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)).
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