Human c-fgr gene does not contain coding sequence for actin-like protein

Makoto Nishizawa, Kentaro Senba, Tadashi Yamamoto, Kumao Toyoshima

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

fgr is a member of the protein kinase oncogene family and was found to have the highest homology to yes gene among the members of the family. Using a v-yes probe, a molecular clone of human c-fgr locus was isolated from a genomic library. Nucleotide sequence determination revealed that the actin gene-like sequence found in v-fgr gene was absent at the corresponding position of the c-fgr gene. Thus, the v-fgr gene product is considered to be a tri-chimeric gene product consisting of viral gag gene and two distinct cellular genes, actin gene and the proto-fgr gene.

Original languageEnglish
Pages (from-to)155-159
Number of pages5
JournalJapanese Journal of Cancer Research
Volume76
Issue number3
Publication statusPublished - 1985 Mar
Externally publishedYes

Fingerprint

Actins
Genes
Proteins
gag Genes
Molecular Probes
Viral Genes
Genomic Library
Oncogenes
Protein Kinases
Sequence Analysis
Clone Cells

Keywords

  • Actin
  • c-fgr
  • Splicing junction

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Human c-fgr gene does not contain coding sequence for actin-like protein. / Nishizawa, Makoto; Senba, Kentaro; Yamamoto, Tadashi; Toyoshima, Kumao.

In: Japanese Journal of Cancer Research, Vol. 76, No. 3, 03.1985, p. 155-159.

Research output: Contribution to journalArticle

Nishizawa, M, Senba, K, Yamamoto, T & Toyoshima, K 1985, 'Human c-fgr gene does not contain coding sequence for actin-like protein', Japanese Journal of Cancer Research, vol. 76, no. 3, pp. 155-159.
Nishizawa, Makoto ; Senba, Kentaro ; Yamamoto, Tadashi ; Toyoshima, Kumao. / Human c-fgr gene does not contain coding sequence for actin-like protein. In: Japanese Journal of Cancer Research. 1985 ; Vol. 76, No. 3. pp. 155-159.
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