Abstract
We examined the hypothesis that activation of the muscle metaboreflex during dynamic exercise would augment influences tending to cause a rise in arginine vasopressin, plasma renin activity, and catecholamines during dynamic exercise in humans. Ten healthy adults performed 30 min of supine cycle ergometer exercise at ~50% of peak oxygen consumption with or without moderate muscle metaboreflex activation by application of 35 mmHg lower body positive pressure (LBPP). Application of LBPP during the first 15 or last 15 min of exercise increased mean arterial blood pressure, plasma lactate concentration, and minute ventilation, indicating an activation of the muscle metaboreflex. These changes were rapidly reversed when LBPP was removed. During exercise at this intensity, LBPP augmented the release of arginine vasopressin and catecholamines but not of plasma renin activity. These results suggest that, although in humans hormonal responses are induced by moderate activation of the muscle metaboreflex during dynamic exercise, the thresholds for these responses may not be uniform among the various glands and hormones.
| Original language | English |
|---|---|
| Pages (from-to) | 300-307 |
| Number of pages | 8 |
| Journal | Journal of Applied Physiology |
| Volume | 88 |
| Issue number | 1 |
| Publication status | Published - 2000 Jan |
| Externally published | Yes |
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Keywords
- Arginine vasopressin
- Exercise
- Lower body positive pressure
- Mean arterial blood pressure
- Muscle metaboreflex
- Plasma renin activity
ASJC Scopus subject areas
- Physiology
- Endocrinology
- Orthopedics and Sports Medicine
- Physical Therapy, Sports Therapy and Rehabilitation
Cite this
Human cardiovascular and humoral responses to moderate muscle activation during dynamic exercise. / Nishiyasu, Takeshi; Nagashima, Kei; Nadel, Ethan R.; Mack, Gary W.
In: Journal of Applied Physiology, Vol. 88, No. 1, 01.2000, p. 300-307.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Human cardiovascular and humoral responses to moderate muscle activation during dynamic exercise
AU - Nishiyasu, Takeshi
AU - Nagashima, Kei
AU - Nadel, Ethan R.
AU - Mack, Gary W.
PY - 2000/1
Y1 - 2000/1
N2 - We examined the hypothesis that activation of the muscle metaboreflex during dynamic exercise would augment influences tending to cause a rise in arginine vasopressin, plasma renin activity, and catecholamines during dynamic exercise in humans. Ten healthy adults performed 30 min of supine cycle ergometer exercise at ~50% of peak oxygen consumption with or without moderate muscle metaboreflex activation by application of 35 mmHg lower body positive pressure (LBPP). Application of LBPP during the first 15 or last 15 min of exercise increased mean arterial blood pressure, plasma lactate concentration, and minute ventilation, indicating an activation of the muscle metaboreflex. These changes were rapidly reversed when LBPP was removed. During exercise at this intensity, LBPP augmented the release of arginine vasopressin and catecholamines but not of plasma renin activity. These results suggest that, although in humans hormonal responses are induced by moderate activation of the muscle metaboreflex during dynamic exercise, the thresholds for these responses may not be uniform among the various glands and hormones.
AB - We examined the hypothesis that activation of the muscle metaboreflex during dynamic exercise would augment influences tending to cause a rise in arginine vasopressin, plasma renin activity, and catecholamines during dynamic exercise in humans. Ten healthy adults performed 30 min of supine cycle ergometer exercise at ~50% of peak oxygen consumption with or without moderate muscle metaboreflex activation by application of 35 mmHg lower body positive pressure (LBPP). Application of LBPP during the first 15 or last 15 min of exercise increased mean arterial blood pressure, plasma lactate concentration, and minute ventilation, indicating an activation of the muscle metaboreflex. These changes were rapidly reversed when LBPP was removed. During exercise at this intensity, LBPP augmented the release of arginine vasopressin and catecholamines but not of plasma renin activity. These results suggest that, although in humans hormonal responses are induced by moderate activation of the muscle metaboreflex during dynamic exercise, the thresholds for these responses may not be uniform among the various glands and hormones.
KW - Arginine vasopressin
KW - Exercise
KW - Lower body positive pressure
KW - Mean arterial blood pressure
KW - Muscle metaboreflex
KW - Plasma renin activity
UR - http://www.scopus.com/inward/record.url?scp=0033977717&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033977717&partnerID=8YFLogxK
M3 - Article
C2 - 10642393
AN - SCOPUS:0033977717
VL - 88
SP - 300
EP - 307
JO - Journal of Applied Physiology Respiratory Environmental and Exercise Physiology
JF - Journal of Applied Physiology Respiratory Environmental and Exercise Physiology
SN - 8750-7587
IS - 1
ER -