Hydroxyapatite containing immobilized collagen and fibronectin promotes bone regeneration

Tomonori Matsuno, Eiji Uchimura, Tadao Ohno, Tazuko Satoh, Yu Sogo, Atsuo Ito, Atsushi Yamazaki, Yusuke Ishikawa, Nao Kondo, Noboru Ichinose

Research output: Contribution to journalReview article

6 Citations (Scopus)

Abstract

Hydroxyapatite (HA) is often used for bone tissue engineering. In this study, we evaluated a novel method for preparing HA containing immobilized collagen and fibronectin (HICF). We examined the ability of this material to promote bone regeneration in vitro and in vivo. Cell pseudopodia were grown on a HICF disk in vitro. Numerous points of new bone formation were observed around HICF granules at 4 weeks in vivo. These results indicate that HICF provides a surface that promotes bone regeneration.

Original languageEnglish
Pages (from-to)330-331
Number of pages2
JournalInternational Congress Series
Volume1284
DOIs
Publication statusPublished - 2005 Sep

Keywords

  • Bone regeneration
  • Collagen
  • Fibronectin
  • Hydroxyapatite
  • Immobilize

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Matsuno, T., Uchimura, E., Ohno, T., Satoh, T., Sogo, Y., Ito, A., Yamazaki, A., Ishikawa, Y., Kondo, N., & Ichinose, N. (2005). Hydroxyapatite containing immobilized collagen and fibronectin promotes bone regeneration. International Congress Series, 1284, 330-331. https://doi.org/10.1016/j.ics.2005.06.011