Image-based computational hemodynamics of distal aortic arch recoarctation following the Norwood procedure

J. L. Liu, K. Itatani, R. Shiurba, T. Miyakoshi, Y. Qian, A. Murakami, K. Miyaji, Mitsuo Umezu

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    7 Citations (Scopus)

    Abstract

    Currently, few applications of computational hemodynamics predict outcomes after palliative surgery for congenital heart defects such as hypolastic left heart syndrome in infants. Here, we report on three-dimensional imaging methods for modeling recoarctation that commonly occurs in the distal aortic arch following the Norwood procedure. We used computer-aided design to simulate seven stages of increasing stenosis, analyze the resulting hemodynamics, and visualize the impairment of blood flow. A disproportionate drop in pressure occurred when stenosis reached 20% of the cross-sectional area of the descending aorta. The corresponding decrease in blood flow in the descending aorta was relatively small, however. Accordingly our findings suggest a reasonable approach to this phenomenon is watchful waiting rather than immediate surgical intervention. Such patient-specific predictions appear to be valuable for minimizing the risks of corrective surgery. These methods also may be applied to procedures for alleviating other congenital heart defects.

    Original languageEnglish
    Title of host publicationProceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011
    Pages318-323
    Number of pages6
    Volume1
    DOIs
    Publication statusPublished - 2011
    Event2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011 - Shanghai
    Duration: 2011 Oct 152011 Oct 17

    Other

    Other2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011
    CityShanghai
    Period11/10/1511/10/17

    Fingerprint

    Norwood Procedures
    Hemodynamics
    Arches
    Thoracic Aorta
    Congenital Heart Defects
    Surgery
    Pathologic Constriction
    Blood
    Watchful Waiting
    Computer-Aided Design
    Defects
    Three-Dimensional Imaging
    Palliative Care
    Computer aided design
    Imaging techniques
    Pressure

    Keywords

    • computational fluid dynamics
    • computer-aided design
    • hemodynamics
    • medical imaging
    • Norwood procedure
    • recoarctation

    ASJC Scopus subject areas

    • Biomedical Engineering
    • Health Informatics
    • Health Information Management

    Cite this

    Liu, J. L., Itatani, K., Shiurba, R., Miyakoshi, T., Qian, Y., Murakami, A., ... Umezu, M. (2011). Image-based computational hemodynamics of distal aortic arch recoarctation following the Norwood procedure. In Proceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011 (Vol. 1, pp. 318-323). [6098269] https://doi.org/10.1109/BMEI.2011.6098269

    Image-based computational hemodynamics of distal aortic arch recoarctation following the Norwood procedure. / Liu, J. L.; Itatani, K.; Shiurba, R.; Miyakoshi, T.; Qian, Y.; Murakami, A.; Miyaji, K.; Umezu, Mitsuo.

    Proceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011. Vol. 1 2011. p. 318-323 6098269.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Liu, JL, Itatani, K, Shiurba, R, Miyakoshi, T, Qian, Y, Murakami, A, Miyaji, K & Umezu, M 2011, Image-based computational hemodynamics of distal aortic arch recoarctation following the Norwood procedure. in Proceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011. vol. 1, 6098269, pp. 318-323, 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011, Shanghai, 11/10/15. https://doi.org/10.1109/BMEI.2011.6098269
    Liu JL, Itatani K, Shiurba R, Miyakoshi T, Qian Y, Murakami A et al. Image-based computational hemodynamics of distal aortic arch recoarctation following the Norwood procedure. In Proceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011. Vol. 1. 2011. p. 318-323. 6098269 https://doi.org/10.1109/BMEI.2011.6098269
    Liu, J. L. ; Itatani, K. ; Shiurba, R. ; Miyakoshi, T. ; Qian, Y. ; Murakami, A. ; Miyaji, K. ; Umezu, Mitsuo. / Image-based computational hemodynamics of distal aortic arch recoarctation following the Norwood procedure. Proceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011. Vol. 1 2011. pp. 318-323
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