Image-based computational hemodynamics of distal aortic arch recoarctation following the Norwood procedure

J. L. Liu, K. Itatani, R. Shiurba, T. Miyakoshi, Y. Qian, A. Murakami, K. Miyaji, M. Umezu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Citations (Scopus)

Abstract

Currently, few applications of computational hemodynamics predict outcomes after palliative surgery for congenital heart defects such as hypolastic left heart syndrome in infants. Here, we report on three-dimensional imaging methods for modeling recoarctation that commonly occurs in the distal aortic arch following the Norwood procedure. We used computer-aided design to simulate seven stages of increasing stenosis, analyze the resulting hemodynamics, and visualize the impairment of blood flow. A disproportionate drop in pressure occurred when stenosis reached 20% of the cross-sectional area of the descending aorta. The corresponding decrease in blood flow in the descending aorta was relatively small, however. Accordingly our findings suggest a reasonable approach to this phenomenon is watchful waiting rather than immediate surgical intervention. Such patient-specific predictions appear to be valuable for minimizing the risks of corrective surgery. These methods also may be applied to procedures for alleviating other congenital heart defects.

Original languageEnglish
Title of host publicationProceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011
Pages318-323
Number of pages6
DOIs
Publication statusPublished - 2011 Dec 1
Event2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011 - Shanghai, China
Duration: 2011 Oct 152011 Oct 17

Publication series

NameProceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011
Volume1

Conference

Conference2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011
CountryChina
CityShanghai
Period11/10/1511/10/17

Keywords

  • Norwood procedure
  • computational fluid dynamics
  • computer-aided design
  • hemodynamics
  • medical imaging
  • recoarctation

ASJC Scopus subject areas

  • Biomedical Engineering
  • Health Informatics
  • Health Information Management

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  • Cite this

    Liu, J. L., Itatani, K., Shiurba, R., Miyakoshi, T., Qian, Y., Murakami, A., Miyaji, K., & Umezu, M. (2011). Image-based computational hemodynamics of distal aortic arch recoarctation following the Norwood procedure. In Proceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011 (pp. 318-323). [6098269] (Proceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011; Vol. 1). https://doi.org/10.1109/BMEI.2011.6098269