Imaging of monochromatic beams by measuring secondary electron bremsstrahlung for carbon-ion therapy using a pinhole x-ray camera

Mitsutaka Yamaguchi*, Yuto Nagao, Koki Ando, Seiichi Yamamoto, Makoto Sakai, Raj Kumar Parajuli, Kazuo Arakawa, Naoki Kawachi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)

Abstract

A feasibility study on the imaging of monochromatic carbon-ion beams for carbon-ion therapy was performed. The evaluation was based on Monte Carlo simulations and beam-irradiation experiments, using a pinhole x-ray camera, which measured secondary electron bremsstrahlung (SEB). The simulation results indicated that the trajectories of the carbon-ion beams with injection energies of 278, 249 and 218 MeV/u in a water phantom, were clearly imaged by measuring the SEB with energies from 30 to 60 keV, using a pinhole camera. The Bragg-peak positions for these three injection energies were located at the positions where the ratios of the counts of SEB acquisitions to the maximum counts were approximately 0.23, 0.26 and 0.29, respectively. Moreover, we experimentally demonstrated that it was possible to identify the Bragg-peak positons, at the positions where the ratios coincided with the simulation results. However, the estimated Bragg-peak positions for the injection energies of 278 and 249 MeV/u were slightly deeper than the expected positions. In conclusion, for both the simulations and experiments, we found that the 25 mm shifts in the Bragg-peak positions can be observed by this method.

Original languageEnglish
Article number045016
JournalPhysics in Medicine and Biology
Volume63
Issue number4
DOIs
Publication statusPublished - 2018 Feb 15
Externally publishedYes

Keywords

  • beam-trajectory imaging
  • Bragg-peak position estimation
  • carbon-ion therapy
  • Monte Carlo simulation
  • pinhole camera
  • secondary electron bremsstrahlung

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

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