Implications for the establishment of accelerated fatigue test protocols for prosthetic heart valves

Kiyotaka Iwasaki, Mitsuo Umezu, Kazuo Iijima, Kou Imachi

    Research output: Contribution to journalArticle

    4 Citations (Scopus)

    Abstract

    The goal of this research is to establish a reliable methodology for accelerated fatigue tests of prosthetic heart valves. A polymer valve was the subject, and the influence of various drive parameters on durability was investigated in three different machines. Valve lifetime was notably shortened by increasing the cyclic rate or stroke even though the maximum pressure difference at valve closure was maintained at 120 mm Hg. These results demonstrate that adjustment of the maximum transvalvular pressure is not sufficient to ensure tests are conducted under the same conditions and indicate that measurement of the dynamic load would be more efficacious. Moreover, the locations of tears sustained in the accelerated tests differed from those encountered in an animal experiment although in both cases the locations were entirely consistent with the areas of strain concentration revealed by finite element analysis. These findings should be discussed during a revision of ISO 5840.

    Original languageEnglish
    Pages (from-to)420-429
    Number of pages10
    JournalArtificial Organs
    Volume26
    Issue number5
    DOIs
    Publication statusPublished - 2002

    Fingerprint

    Heart valve prostheses
    Heart Valves
    Fatigue
    Fatigue of materials
    Pressure
    Finite Element Analysis
    Dynamic loads
    Tears
    Polymers
    Animals
    Durability
    Stroke
    Finite element method
    Research
    Experiments

    Keywords

    • Accelerated fatigue test
    • Durability
    • Fracture
    • ISO 5840
    • Jellyfish valve
    • Polymer valve

    ASJC Scopus subject areas

    • Biophysics

    Cite this

    Implications for the establishment of accelerated fatigue test protocols for prosthetic heart valves. / Iwasaki, Kiyotaka; Umezu, Mitsuo; Iijima, Kazuo; Imachi, Kou.

    In: Artificial Organs, Vol. 26, No. 5, 2002, p. 420-429.

    Research output: Contribution to journalArticle

    @article{57bee9aa168449ceb432e7a4c39fae53,
    title = "Implications for the establishment of accelerated fatigue test protocols for prosthetic heart valves",
    abstract = "The goal of this research is to establish a reliable methodology for accelerated fatigue tests of prosthetic heart valves. A polymer valve was the subject, and the influence of various drive parameters on durability was investigated in three different machines. Valve lifetime was notably shortened by increasing the cyclic rate or stroke even though the maximum pressure difference at valve closure was maintained at 120 mm Hg. These results demonstrate that adjustment of the maximum transvalvular pressure is not sufficient to ensure tests are conducted under the same conditions and indicate that measurement of the dynamic load would be more efficacious. Moreover, the locations of tears sustained in the accelerated tests differed from those encountered in an animal experiment although in both cases the locations were entirely consistent with the areas of strain concentration revealed by finite element analysis. These findings should be discussed during a revision of ISO 5840.",
    keywords = "Accelerated fatigue test, Durability, Fracture, ISO 5840, Jellyfish valve, Polymer valve",
    author = "Kiyotaka Iwasaki and Mitsuo Umezu and Kazuo Iijima and Kou Imachi",
    year = "2002",
    doi = "10.1046/j.1525-1594.2002.06956.x",
    language = "English",
    volume = "26",
    pages = "420--429",
    journal = "Artificial Organs",
    issn = "0160-564X",
    publisher = "Wiley-Blackwell",
    number = "5",

    }

    TY - JOUR

    T1 - Implications for the establishment of accelerated fatigue test protocols for prosthetic heart valves

    AU - Iwasaki, Kiyotaka

    AU - Umezu, Mitsuo

    AU - Iijima, Kazuo

    AU - Imachi, Kou

    PY - 2002

    Y1 - 2002

    N2 - The goal of this research is to establish a reliable methodology for accelerated fatigue tests of prosthetic heart valves. A polymer valve was the subject, and the influence of various drive parameters on durability was investigated in three different machines. Valve lifetime was notably shortened by increasing the cyclic rate or stroke even though the maximum pressure difference at valve closure was maintained at 120 mm Hg. These results demonstrate that adjustment of the maximum transvalvular pressure is not sufficient to ensure tests are conducted under the same conditions and indicate that measurement of the dynamic load would be more efficacious. Moreover, the locations of tears sustained in the accelerated tests differed from those encountered in an animal experiment although in both cases the locations were entirely consistent with the areas of strain concentration revealed by finite element analysis. These findings should be discussed during a revision of ISO 5840.

    AB - The goal of this research is to establish a reliable methodology for accelerated fatigue tests of prosthetic heart valves. A polymer valve was the subject, and the influence of various drive parameters on durability was investigated in three different machines. Valve lifetime was notably shortened by increasing the cyclic rate or stroke even though the maximum pressure difference at valve closure was maintained at 120 mm Hg. These results demonstrate that adjustment of the maximum transvalvular pressure is not sufficient to ensure tests are conducted under the same conditions and indicate that measurement of the dynamic load would be more efficacious. Moreover, the locations of tears sustained in the accelerated tests differed from those encountered in an animal experiment although in both cases the locations were entirely consistent with the areas of strain concentration revealed by finite element analysis. These findings should be discussed during a revision of ISO 5840.

    KW - Accelerated fatigue test

    KW - Durability

    KW - Fracture

    KW - ISO 5840

    KW - Jellyfish valve

    KW - Polymer valve

    UR - http://www.scopus.com/inward/record.url?scp=0036098339&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=0036098339&partnerID=8YFLogxK

    U2 - 10.1046/j.1525-1594.2002.06956.x

    DO - 10.1046/j.1525-1594.2002.06956.x

    M3 - Article

    C2 - 12000438

    AN - SCOPUS:0036098339

    VL - 26

    SP - 420

    EP - 429

    JO - Artificial Organs

    JF - Artificial Organs

    SN - 0160-564X

    IS - 5

    ER -