Improvement of fabrication process of vacuum formed valves for ventricular assist device

M. Umezu, M. Ranawake, T. Nakayama, K. Kobayashi, T. Kido, C. Nojiri, T. Kijima, T. Fujimoto, T. Akutsu

Research output: Contribution to journalArticlepeer-review


In order to provide an inexpensive ventricular assist device (VAD), we developed a 20mL-VAD which was followed by Prof. Kolff's design, but two problems were found; 1) Big amount of regurgitation through inlet bileaflet valve. 2) High resistance of outlet trileaflet valve. Following trials were carried out to settle them; 1) In the manufacturing process of the bileaflet valve, elastic material was used instead of hard plastic plate. Then, regurgitation could be reduced to 1/6. Moreover, total manufacturing process could be dramatically simplified. 2) In the manufacturing process of the trileaflet valve, leaflet thickness was well controlled around 0.2 mm with the aid of a special ring which was located around the valve mold. Then, lower resistance could be achieved by a thin (0.19mm) leaflet valve. Moreover, all valves could be passed the durability testing for 14 days. These data is helpful towards a pre-production stage of the VAD development.

Original languageEnglish
Pages (from-to)43-47
Number of pages5
JournalJapanese Journal of Artificial Organs
Issue number1
Publication statusPublished - 1996 May 14


  • Bileaflet valve
  • Regurgitation
  • Trileaflet valve
  • VAD
  • Vacuum forming

ASJC Scopus subject areas

  • Biophysics

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