Improvement of filtration performance using self-tuning of flow resistance

Dong Hyun Yoon, Yeon Kyoung Bahk, Bong Hyun Kwon, Seong Sik Kim, Yong Deok Kim, Takahiro Arakawa, Jeung Sang Go, Shuichi Shoji

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Abstract

In this paper, we present the filtration of a liquid sample from polystyrene microparticles analogous to the separation of a biological liquid from mixed particles such as whole blood. The proposed self-tuning of flow resistance can prevent the excessive clogging of microparticles in the microfilter by allowing the automatic change of the flow direction when the microfilter is clogged. Numerically, at about 80% of the clogging of microparticles in the pillar channel, the sample flow is regulated suddenly to the bypass channel. Experimentally, the clogging behavior at the five successive pillar channels and the self-tuning of flow are compared by measuring the clogging area and volume with time. Also, the microfilter array connected in a series can provide an increase in the sample volume proportionally without excessive pressure build-up. This implies the potential to reduce cell fracture in the filtration of biological cells.

Original languageEnglish
Article number017201
JournalJapanese journal of applied physics
Volume50
Issue number1
DOIs
Publication statusPublished - 2011 Jan 1

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ASJC Scopus subject areas

  • Engineering(all)
  • Physics and Astronomy(all)

Cite this

Yoon, D. H., Bahk, Y. K., Kwon, B. H., Kim, S. S., Kim, Y. D., Arakawa, T., Go, J. S., & Shoji, S. (2011). Improvement of filtration performance using self-tuning of flow resistance. Japanese journal of applied physics, 50(1), [017201]. https://doi.org/10.1143/JJAP.50.017201