In vitro calcification of UHMWPE/PU composite membrane

Z. G. Tang, S. H. Teoh, W. McFarlane, L. A. Poole-Warren, Mitsuo Umezu

    Research output: Contribution to journalArticle

    11 Citations (Scopus)

    Abstract

    Polyurethane composite made from biaxially drawn ultrahigh molecular weight polyethylene (BDUHMWPE) is likely an alternative for polyurethane currently being plagued for medical applications. In this study, an in vitro calcification protocol was used to determine the relative resistance to calcification of the composite membranes. The results demonstrated that the composite membranes were susceptible to extrinsic calcification that was closely related to the matrix polyurethane material used. The calcification of the composite was different from that of the solution cast polyurethane membranes. The incorporation of hydrophobic reinforcement BDUHMWPE effectively postponed the calcification. The differences of calcification between composite and polyurethane were greatly due to the differences in surface structures and properties of the as-cast polyurethane.

    Original languageEnglish
    Pages (from-to)149-152
    Number of pages4
    JournalMaterials Science and Engineering C
    Volume20
    Issue number1-2
    DOIs
    Publication statusPublished - 2002 May 31

    Fingerprint

    calcification
    Ultrahigh molecular weight polyethylenes
    Polyurethanes
    Composite membranes
    membranes
    composite materials
    casts
    polyethylenes
    molecular weight
    Composite materials
    Medical applications
    reinforcement
    Surface structure
    Surface properties
    ultra-high molecular weight polyethylene
    Reinforcement
    Membranes
    matrices

    Keywords

    • Biaxially drawn ultrahigh molecular weight polyethylene
    • Composite
    • In vitro calcification
    • Polyether polyurethane

    ASJC Scopus subject areas

    • Biomaterials

    Cite this

    In vitro calcification of UHMWPE/PU composite membrane. / Tang, Z. G.; Teoh, S. H.; McFarlane, W.; Poole-Warren, L. A.; Umezu, Mitsuo.

    In: Materials Science and Engineering C, Vol. 20, No. 1-2, 31.05.2002, p. 149-152.

    Research output: Contribution to journalArticle

    Tang, Z. G. ; Teoh, S. H. ; McFarlane, W. ; Poole-Warren, L. A. ; Umezu, Mitsuo. / In vitro calcification of UHMWPE/PU composite membrane. In: Materials Science and Engineering C. 2002 ; Vol. 20, No. 1-2. pp. 149-152.
    @article{188c4400e3fb42e3ade5e481ef822f7b,
    title = "In vitro calcification of UHMWPE/PU composite membrane",
    abstract = "Polyurethane composite made from biaxially drawn ultrahigh molecular weight polyethylene (BDUHMWPE) is likely an alternative for polyurethane currently being plagued for medical applications. In this study, an in vitro calcification protocol was used to determine the relative resistance to calcification of the composite membranes. The results demonstrated that the composite membranes were susceptible to extrinsic calcification that was closely related to the matrix polyurethane material used. The calcification of the composite was different from that of the solution cast polyurethane membranes. The incorporation of hydrophobic reinforcement BDUHMWPE effectively postponed the calcification. The differences of calcification between composite and polyurethane were greatly due to the differences in surface structures and properties of the as-cast polyurethane.",
    keywords = "Biaxially drawn ultrahigh molecular weight polyethylene, Composite, In vitro calcification, Polyether polyurethane",
    author = "Tang, {Z. G.} and Teoh, {S. H.} and W. McFarlane and Poole-Warren, {L. A.} and Mitsuo Umezu",
    year = "2002",
    month = "5",
    day = "31",
    doi = "10.1016/S0928-4931(02)00025-5",
    language = "English",
    volume = "20",
    pages = "149--152",
    journal = "Materials Science and Engineering C",
    issn = "0928-4931",
    publisher = "Elsevier BV",
    number = "1-2",

    }

    TY - JOUR

    T1 - In vitro calcification of UHMWPE/PU composite membrane

    AU - Tang, Z. G.

    AU - Teoh, S. H.

    AU - McFarlane, W.

    AU - Poole-Warren, L. A.

    AU - Umezu, Mitsuo

    PY - 2002/5/31

    Y1 - 2002/5/31

    N2 - Polyurethane composite made from biaxially drawn ultrahigh molecular weight polyethylene (BDUHMWPE) is likely an alternative for polyurethane currently being plagued for medical applications. In this study, an in vitro calcification protocol was used to determine the relative resistance to calcification of the composite membranes. The results demonstrated that the composite membranes were susceptible to extrinsic calcification that was closely related to the matrix polyurethane material used. The calcification of the composite was different from that of the solution cast polyurethane membranes. The incorporation of hydrophobic reinforcement BDUHMWPE effectively postponed the calcification. The differences of calcification between composite and polyurethane were greatly due to the differences in surface structures and properties of the as-cast polyurethane.

    AB - Polyurethane composite made from biaxially drawn ultrahigh molecular weight polyethylene (BDUHMWPE) is likely an alternative for polyurethane currently being plagued for medical applications. In this study, an in vitro calcification protocol was used to determine the relative resistance to calcification of the composite membranes. The results demonstrated that the composite membranes were susceptible to extrinsic calcification that was closely related to the matrix polyurethane material used. The calcification of the composite was different from that of the solution cast polyurethane membranes. The incorporation of hydrophobic reinforcement BDUHMWPE effectively postponed the calcification. The differences of calcification between composite and polyurethane were greatly due to the differences in surface structures and properties of the as-cast polyurethane.

    KW - Biaxially drawn ultrahigh molecular weight polyethylene

    KW - Composite

    KW - In vitro calcification

    KW - Polyether polyurethane

    UR - http://www.scopus.com/inward/record.url?scp=0037205336&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=0037205336&partnerID=8YFLogxK

    U2 - 10.1016/S0928-4931(02)00025-5

    DO - 10.1016/S0928-4931(02)00025-5

    M3 - Article

    VL - 20

    SP - 149

    EP - 152

    JO - Materials Science and Engineering C

    JF - Materials Science and Engineering C

    SN - 0928-4931

    IS - 1-2

    ER -