In vitro calcification of UHMWPE/PU composite membrane

Z. G. Tang, S. H. Teoh, W. McFarlane, L. A. Poole-Warren, Mitsuo Umezu

    Research output: Contribution to journalArticle

    11 Citations (Scopus)

    Abstract

    Polyurethane composite made from biaxially drawn ultrahigh molecular weight polyethylene (BDUHMWPE) is likely an alternative for polyurethane currently being plagued for medical applications. In this study, an in vitro calcification protocol was used to determine the relative resistance to calcification of the composite membranes. The results demonstrated that the composite membranes were susceptible to extrinsic calcification that was closely related to the matrix polyurethane material used. The calcification of the composite was different from that of the solution cast polyurethane membranes. The incorporation of hydrophobic reinforcement BDUHMWPE effectively postponed the calcification. The differences of calcification between composite and polyurethane were greatly due to the differences in surface structures and properties of the as-cast polyurethane.

    Original languageEnglish
    Pages (from-to)149-152
    Number of pages4
    JournalMaterials Science and Engineering C
    Volume20
    Issue number1-2
    DOIs
    Publication statusPublished - 2002 May 31

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    Keywords

    • Biaxially drawn ultrahigh molecular weight polyethylene
    • Composite
    • In vitro calcification
    • Polyether polyurethane

    ASJC Scopus subject areas

    • Biomaterials

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