In vitro investigation of an electrically actuated antireflux valve for a multiuse contrast agent injection system

Takanobu Yagi, Mitsuo Umezu

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVE. The purpose of this study was to determine the capability of a newly developed antireflux valve for a multiuse contrast agent injection system. MATERIALS AND METHODS. Multiuse contrast agent injection systems require an antireflux valve to eliminate the risk of cross-patient blood contamination. An electrically actuated antireflux valve developed for this purpose can control risk of contamination because it is under forced control and surveillance. In this study, the injection system was connected to a pulsatile circulation system that reproduced an aortic flow environment in vitro. The transvalvular pressure difference was measured, and flow dynamics during valve opening and closing were visualized by high-speed flow visualization. A total of 30 injection conditions were tested, which included two catheters (6- A nd 2-French diameter), five contrast agent concentrations (100%, 90%, 50%, 10%, and 0%), and a wide range of flow rates (0.1-25.0 mL/s). RESULTS. The transvalvular pressure difference and flow dynamics during valve opening and closing were characterized. Just before valve opening, a minimum transvalvular pressure difference of 0.20 MPa (1500 mm Hg) was confirmed. The positive pressure difference prevented regurgitation during valve opening. During valve closing, the front of the backflow was monitored continuously, and we confirmed that the front failed to reach the valve before complete closure. CONCLUSION. This study provided proof of concept for an electrically actuated antireflux valve to be used in a multiuse contrast agent injection system.

Original languageEnglish
Pages (from-to)795-799
Number of pages5
JournalAmerican Journal of Roentgenology
Volume215
Issue number4
DOIs
Publication statusPublished - 2020 Oct

Keywords

  • Contrast Medium Injection
  • Flow Visualization
  • Multiuse
  • Valve

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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