In vitro investigation of opening behavior and hydrodynamics of bileaflet valves in the mitral position

Zhonggang Feng, Takao Nakamura, Tetsuo Fujimoto, Mitsuo Umezu

    Research output: Contribution to journalArticle

    24 Citations (Scopus)

    Abstract

    The performance of four 25 mm bileaflet valves of different designs was evaluated in the mitral position of our own pulse simulator. With the aid of a high-speed video camera, it was demonstrated that both the St. Jude Medical (SJM) valve (Hemodynamic Plus [HP] Series, St. Jude Medical, Inc., St. Paul, MN, U.S.A.) and the CM valve (CarboMedics, Inc., Austin, TX, U.S.A.) were able to open fully and that the CM valve fluttered much more vigorously at the fully open position than did the SJM HP valve. Conversely, neither the ATS valve (ATS Medical, Inc., Minneapolis, MN, U.S.A.) nor the On-X valve (Medical Carbon Research Institute, Austin, TX, U.S.A.) exhibited movement to a fully open configuration. The overall average opening angles of the ATS and the On-X, on 3, 4, and 5 L/min flow rate for a heart rate of 70 bpm and 5, 6, and 7 L/min for 100 bpm, were 74.8 degrees and 81.6 degrees, respectively, whereas their design opening angles were 85 degrees and 90 degrees. Pressure drops across the CM and the ATS were consistently higher than those of the On-X and the SJM HP. Closing volumes for all the valves were below 8% for a heart rate of 70 bpm. This in vitro investigation yielded the following conclusions: The ATS and On-X valves are not able to open fully in the mitral position, but this does not impair their normal function; both a larger orifice diameter and a large opening angle can decrease the pressure drop; in general, the On-X valve achieves its design goals in this experiment (i.e., it produces a lower pressure drop and lower closing volume by virtue of its large orifice and high-profile design); however, the hinge flow in the non-fully open state should be investigated further.

    Original languageEnglish
    Pages (from-to)32-39
    Number of pages8
    JournalArtificial Organs
    Volume26
    Issue number1
    DOIs
    Publication statusPublished - 2002

    Fingerprint

    Hydrodynamics
    Closing Volume
    Mitral Valve
    Hemodynamics
    Pressure drop
    Pressure
    Orifices
    Heart Rate
    Pulse
    Biomedical Research
    High speed cameras
    Video cameras
    Hinges
    Carbon
    Simulators
    Flow rate
    In Vitro Techniques
    austin
    Experiments

    Keywords

    • Bileaflet valve
    • In vitro test
    • Leaflet movement
    • Mitral position
    • Non-fully open

    ASJC Scopus subject areas

    • Biophysics

    Cite this

    In vitro investigation of opening behavior and hydrodynamics of bileaflet valves in the mitral position. / Feng, Zhonggang; Nakamura, Takao; Fujimoto, Tetsuo; Umezu, Mitsuo.

    In: Artificial Organs, Vol. 26, No. 1, 2002, p. 32-39.

    Research output: Contribution to journalArticle

    Feng, Zhonggang ; Nakamura, Takao ; Fujimoto, Tetsuo ; Umezu, Mitsuo. / In vitro investigation of opening behavior and hydrodynamics of bileaflet valves in the mitral position. In: Artificial Organs. 2002 ; Vol. 26, No. 1. pp. 32-39.
    @article{449f7448ce594830acefb9097cbeeeb7,
    title = "In vitro investigation of opening behavior and hydrodynamics of bileaflet valves in the mitral position",
    abstract = "The performance of four 25 mm bileaflet valves of different designs was evaluated in the mitral position of our own pulse simulator. With the aid of a high-speed video camera, it was demonstrated that both the St. Jude Medical (SJM) valve (Hemodynamic Plus [HP] Series, St. Jude Medical, Inc., St. Paul, MN, U.S.A.) and the CM valve (CarboMedics, Inc., Austin, TX, U.S.A.) were able to open fully and that the CM valve fluttered much more vigorously at the fully open position than did the SJM HP valve. Conversely, neither the ATS valve (ATS Medical, Inc., Minneapolis, MN, U.S.A.) nor the On-X valve (Medical Carbon Research Institute, Austin, TX, U.S.A.) exhibited movement to a fully open configuration. The overall average opening angles of the ATS and the On-X, on 3, 4, and 5 L/min flow rate for a heart rate of 70 bpm and 5, 6, and 7 L/min for 100 bpm, were 74.8 degrees and 81.6 degrees, respectively, whereas their design opening angles were 85 degrees and 90 degrees. Pressure drops across the CM and the ATS were consistently higher than those of the On-X and the SJM HP. Closing volumes for all the valves were below 8{\%} for a heart rate of 70 bpm. This in vitro investigation yielded the following conclusions: The ATS and On-X valves are not able to open fully in the mitral position, but this does not impair their normal function; both a larger orifice diameter and a large opening angle can decrease the pressure drop; in general, the On-X valve achieves its design goals in this experiment (i.e., it produces a lower pressure drop and lower closing volume by virtue of its large orifice and high-profile design); however, the hinge flow in the non-fully open state should be investigated further.",
    keywords = "Bileaflet valve, In vitro test, Leaflet movement, Mitral position, Non-fully open",
    author = "Zhonggang Feng and Takao Nakamura and Tetsuo Fujimoto and Mitsuo Umezu",
    year = "2002",
    doi = "10.1046/j.1525-1594.2002.06833.x",
    language = "English",
    volume = "26",
    pages = "32--39",
    journal = "Artificial Organs",
    issn = "0160-564X",
    publisher = "Wiley-Blackwell",
    number = "1",

    }

    TY - JOUR

    T1 - In vitro investigation of opening behavior and hydrodynamics of bileaflet valves in the mitral position

    AU - Feng, Zhonggang

    AU - Nakamura, Takao

    AU - Fujimoto, Tetsuo

    AU - Umezu, Mitsuo

    PY - 2002

    Y1 - 2002

    N2 - The performance of four 25 mm bileaflet valves of different designs was evaluated in the mitral position of our own pulse simulator. With the aid of a high-speed video camera, it was demonstrated that both the St. Jude Medical (SJM) valve (Hemodynamic Plus [HP] Series, St. Jude Medical, Inc., St. Paul, MN, U.S.A.) and the CM valve (CarboMedics, Inc., Austin, TX, U.S.A.) were able to open fully and that the CM valve fluttered much more vigorously at the fully open position than did the SJM HP valve. Conversely, neither the ATS valve (ATS Medical, Inc., Minneapolis, MN, U.S.A.) nor the On-X valve (Medical Carbon Research Institute, Austin, TX, U.S.A.) exhibited movement to a fully open configuration. The overall average opening angles of the ATS and the On-X, on 3, 4, and 5 L/min flow rate for a heart rate of 70 bpm and 5, 6, and 7 L/min for 100 bpm, were 74.8 degrees and 81.6 degrees, respectively, whereas their design opening angles were 85 degrees and 90 degrees. Pressure drops across the CM and the ATS were consistently higher than those of the On-X and the SJM HP. Closing volumes for all the valves were below 8% for a heart rate of 70 bpm. This in vitro investigation yielded the following conclusions: The ATS and On-X valves are not able to open fully in the mitral position, but this does not impair their normal function; both a larger orifice diameter and a large opening angle can decrease the pressure drop; in general, the On-X valve achieves its design goals in this experiment (i.e., it produces a lower pressure drop and lower closing volume by virtue of its large orifice and high-profile design); however, the hinge flow in the non-fully open state should be investigated further.

    AB - The performance of four 25 mm bileaflet valves of different designs was evaluated in the mitral position of our own pulse simulator. With the aid of a high-speed video camera, it was demonstrated that both the St. Jude Medical (SJM) valve (Hemodynamic Plus [HP] Series, St. Jude Medical, Inc., St. Paul, MN, U.S.A.) and the CM valve (CarboMedics, Inc., Austin, TX, U.S.A.) were able to open fully and that the CM valve fluttered much more vigorously at the fully open position than did the SJM HP valve. Conversely, neither the ATS valve (ATS Medical, Inc., Minneapolis, MN, U.S.A.) nor the On-X valve (Medical Carbon Research Institute, Austin, TX, U.S.A.) exhibited movement to a fully open configuration. The overall average opening angles of the ATS and the On-X, on 3, 4, and 5 L/min flow rate for a heart rate of 70 bpm and 5, 6, and 7 L/min for 100 bpm, were 74.8 degrees and 81.6 degrees, respectively, whereas their design opening angles were 85 degrees and 90 degrees. Pressure drops across the CM and the ATS were consistently higher than those of the On-X and the SJM HP. Closing volumes for all the valves were below 8% for a heart rate of 70 bpm. This in vitro investigation yielded the following conclusions: The ATS and On-X valves are not able to open fully in the mitral position, but this does not impair their normal function; both a larger orifice diameter and a large opening angle can decrease the pressure drop; in general, the On-X valve achieves its design goals in this experiment (i.e., it produces a lower pressure drop and lower closing volume by virtue of its large orifice and high-profile design); however, the hinge flow in the non-fully open state should be investigated further.

    KW - Bileaflet valve

    KW - In vitro test

    KW - Leaflet movement

    KW - Mitral position

    KW - Non-fully open

    UR - http://www.scopus.com/inward/record.url?scp=0036118796&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=0036118796&partnerID=8YFLogxK

    U2 - 10.1046/j.1525-1594.2002.06833.x

    DO - 10.1046/j.1525-1594.2002.06833.x

    M3 - Article

    C2 - 11872009

    AN - SCOPUS:0036118796

    VL - 26

    SP - 32

    EP - 39

    JO - Artificial Organs

    JF - Artificial Organs

    SN - 0160-564X

    IS - 1

    ER -