In vivo measurement of superoxide anion radical by means of electrode modified with electropolymerized iron porphyrin

Satoshi Tsutsui; Masahiro Namba; Masuhide Ishikawa; Katsuya Eguchi; Aritomo Yamaguchi; Kenichi Oyaizu; Makoto Yuasa

In vivo measurement of superoxide anion radical by means of electrode modified with electropolymerized iron porphyrin

Satoshi Tsutsui^*, Masahiro Namba, Masuhide Ishikawa, Katsuya Eguchi, Aritomo Yamaguchi, Kenichi Oyaizu, Makoto Yuasa

^*Corresponding author for this work

Research output: Contribution to conference › Paper › peer-review

Abstract

Iron meso-tettakis(3-thiofuryl)porphyrin (FeT3ThP) complexes were synthesized and electropolymerized onto a carbon microelectrode. Heparin/polypyrrole membrane, which can be expected for antithrombogenicity and conductivity, was electropolymerized on the porphyrin-modified electrodes. The obtained modified electrodes were applied to a Superoxide anion (O ₂^-̇) sensor to detect the catalytic oxidation current of O₂^-̇. Chronoamperometory revealed that quantitative O₂^-̇ sensing could be performed using the polymerized FeT3 ThP covered with heparin/polypyrrole film with antithrombogenicity.

Original language	English
Pages	1383
Number of pages	1
Publication status	Published - 2005
Externally published	Yes
Event	54th SPSJ Annual Meeting 2005 - Yokohama, Japan Duration: 2005 May 25 → 2005 May 27

Conference

Conference	54th SPSJ Annual Meeting 2005
Country/Territory	Japan
City	Yokohama
Period	05/5/25 → 05/5/27

Keywords

Antithrombogenicity
Heparin
Superoxide anion radical
Superoxide sensor
Tetrathiofurylporphyrin

ASJC Scopus subject areas

Engineering(all)

Cite this

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title = "In vivo measurement of superoxide anion radical by means of electrode modified with electropolymerized iron porphyrin",

abstract = "Iron meso-tettakis(3-thiofuryl)porphyrin (FeT3ThP) complexes were synthesized and electropolymerized onto a carbon microelectrode. Heparin/polypyrrole membrane, which can be expected for antithrombogenicity and conductivity, was electropolymerized on the porphyrin-modified electrodes. The obtained modified electrodes were applied to a Superoxide anion (O 2{\.-}) sensor to detect the catalytic oxidation current of O2{\.-}. Chronoamperometory revealed that quantitative O2{\.-} sensing could be performed using the polymerized FeT3 ThP covered with heparin/polypyrrole film with antithrombogenicity.",

keywords = "Antithrombogenicity, Heparin, Superoxide anion radical, Superoxide sensor, Tetrathiofurylporphyrin",

author = "Satoshi Tsutsui and Masahiro Namba and Masuhide Ishikawa and Katsuya Eguchi and Aritomo Yamaguchi and Kenichi Oyaizu and Makoto Yuasa",

year = "2005",

language = "English",

pages = "1383",

note = "54th SPSJ Annual Meeting 2005 ; Conference date: 25-05-2005 Through 27-05-2005",

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TY - CONF

T1 - In vivo measurement of superoxide anion radical by means of electrode modified with electropolymerized iron porphyrin

AU - Tsutsui, Satoshi

AU - Namba, Masahiro

AU - Ishikawa, Masuhide

AU - Eguchi, Katsuya

AU - Yamaguchi, Aritomo

AU - Oyaizu, Kenichi

AU - Yuasa, Makoto

PY - 2005

Y1 - 2005

N2 - Iron meso-tettakis(3-thiofuryl)porphyrin (FeT3ThP) complexes were synthesized and electropolymerized onto a carbon microelectrode. Heparin/polypyrrole membrane, which can be expected for antithrombogenicity and conductivity, was electropolymerized on the porphyrin-modified electrodes. The obtained modified electrodes were applied to a Superoxide anion (O 2-̇) sensor to detect the catalytic oxidation current of O2-̇. Chronoamperometory revealed that quantitative O2-̇ sensing could be performed using the polymerized FeT3 ThP covered with heparin/polypyrrole film with antithrombogenicity.

AB - Iron meso-tettakis(3-thiofuryl)porphyrin (FeT3ThP) complexes were synthesized and electropolymerized onto a carbon microelectrode. Heparin/polypyrrole membrane, which can be expected for antithrombogenicity and conductivity, was electropolymerized on the porphyrin-modified electrodes. The obtained modified electrodes were applied to a Superoxide anion (O 2-̇) sensor to detect the catalytic oxidation current of O2-̇. Chronoamperometory revealed that quantitative O2-̇ sensing could be performed using the polymerized FeT3 ThP covered with heparin/polypyrrole film with antithrombogenicity.

KW - Antithrombogenicity

KW - Heparin

KW - Superoxide anion radical

KW - Superoxide sensor

KW - Tetrathiofurylporphyrin

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M3 - Paper

AN - SCOPUS:33645642208

SP - 1383

T2 - 54th SPSJ Annual Meeting 2005

Y2 - 25 May 2005 through 27 May 2005

ER -

In vivo measurement of superoxide anion radical by means of electrode modified with electropolymerized iron porphyrin

Abstract

Conference

Keywords

ASJC Scopus subject areas

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