In vivo ultrahigh-resolution ophthalmic optical coherence tomography using Gaussian-shaped supercontinuum

Masahiro Nishiura; Toshihiro Kobayashi; Muneyuki Adachi; Jun Nakanishi; Tokio Ueno; Yasuki Ito; Norihiko Nishizawa

doi:10.1143/JJAP.49.012701

In vivo ultrahigh-resolution ophthalmic optical coherence tomography using Gaussian-shaped supercontinuum

Masahiro Nishiura, Toshihiro Kobayashi, Muneyuki Adachi, Jun Nakanishi, Tokio Ueno, Yasuki Ito, Norihiko Nishizawa^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

We have demonstrated the in vivo ultrahigh-resolution optical coherence tomography (OCT) imaging of the human eye using a Gaussian-shaped supercontinuum source. Using an ultrashort-pulse Ti:sapphire laser and a polarization- maintaining single-mode fiber, a linearly polarized, high-power, low-noise, Gaussian-shaped supercontinuum is generated in the wavelength region from 700 to 950 nm. For ophthalmic imaging, a wideband Gaussian-shaped supercontinuum with a bandwidth of 140nm is generated at a center wavelength of 830 nm. The observed axial resolutions are 2.9 μm in air and 2.1μm in tissue. The generated supercontinuum is combined with a modified ophthalmic OCT system, and sidelobe-free ultrahigh-resolution OCT images of the human retina and cornea are obtained.

Original language	English
Article number	012701
Journal	Japanese journal of applied physics
Volume	49
Issue number	1 Part 1
DOIs	https://doi.org/10.1143/JJAP.49.012701
Publication status	Published - 2010
Externally published	Yes

ASJC Scopus subject areas

Engineering(all)
Physics and Astronomy(all)

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abstract = "We have demonstrated the in vivo ultrahigh-resolution optical coherence tomography (OCT) imaging of the human eye using a Gaussian-shaped supercontinuum source. Using an ultrashort-pulse Ti:sapphire laser and a polarization- maintaining single-mode fiber, a linearly polarized, high-power, low-noise, Gaussian-shaped supercontinuum is generated in the wavelength region from 700 to 950 nm. For ophthalmic imaging, a wideband Gaussian-shaped supercontinuum with a bandwidth of 140nm is generated at a center wavelength of 830 nm. The observed axial resolutions are 2.9 μm in air and 2.1μm in tissue. The generated supercontinuum is combined with a modified ophthalmic OCT system, and sidelobe-free ultrahigh-resolution OCT images of the human retina and cornea are obtained.",

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AU - Nishiura, Masahiro

AU - Kobayashi, Toshihiro

AU - Adachi, Muneyuki

AU - Nakanishi, Jun

AU - Ueno, Tokio

AU - Ito, Yasuki

AU - Nishizawa, Norihiko

PY - 2010

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In vivo ultrahigh-resolution ophthalmic optical coherence tomography using Gaussian-shaped supercontinuum

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