In vivo ultrahigh-resolution ophthalmic optical coherence tomography using Gaussian-shaped supercontinuum

Masahiro Nishiura, Toshihiro Kobayashi, Muneyuki Adachi, Jun Nakanishi, Tokio Ueno, Yasuki Ito, Norihiko Nishizawa

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Abstract

We have demonstrated the in vivo ultrahigh-resolution optical coherence tomography (OCT) imaging of the human eye using a Gaussian-shaped supercontinuum source. Using an ultrashort-pulse Ti:sapphire laser and a polarization- maintaining single-mode fiber, a linearly polarized, high-power, low-noise, Gaussian-shaped supercontinuum is generated in the wavelength region from 700 to 950 nm. For ophthalmic imaging, a wideband Gaussian-shaped supercontinuum with a bandwidth of 140nm is generated at a center wavelength of 830 nm. The observed axial resolutions are 2.9 μm in air and 2.1μm in tissue. The generated supercontinuum is combined with a modified ophthalmic OCT system, and sidelobe-free ultrahigh-resolution OCT images of the human retina and cornea are obtained.

Original languageEnglish
Article number012701
JournalJapanese journal of applied physics
Volume49
Issue number1 Part 1
DOIs
Publication statusPublished - 2010 Apr 19

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ASJC Scopus subject areas

  • Engineering(all)
  • Physics and Astronomy(all)

Cite this

Nishiura, M., Kobayashi, T., Adachi, M., Nakanishi, J., Ueno, T., Ito, Y., & Nishizawa, N. (2010). In vivo ultrahigh-resolution ophthalmic optical coherence tomography using Gaussian-shaped supercontinuum. Japanese journal of applied physics, 49(1 Part 1), [012701]. https://doi.org/10.1143/JJAP.49.012701