Increased cell functionalities with patterned co-cultures utilizing dual thermo-responsive polymer grafted surfaces

Y. Tsuda, A. Kikuchi, A. Nakao, M. Yamato, Y. Sakurai, Mitsuo Umezu, T. Okano

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    The impact of increased cell functionalities with patterned co-cultures was investigated by utilizing thermo-responsive hydrophilic property changes of poly(N-isopropylacrylamide) (PIPAAm). It was observed that regulating transition temperature of PIPAAm produce new culture for co-culture and in recovering co-cultured cell sheets. The cell functions were estimated by altering pattern sizes in the co-culture system. The results show that the stratification of co-cultured cell sheets leads to the creation of novel tissue constructs structurally similar to the native organs and tissues.

    Original languageEnglish
    Title of host publicationTransactions - 7th World Biomaterials Congress
    Pages246
    Number of pages1
    Publication statusPublished - 2004
    EventTransactions - 7th World Biomaterials Congress - Sydney
    Duration: 2004 May 172004 May 21

    Other

    OtherTransactions - 7th World Biomaterials Congress
    CitySydney
    Period04/5/1704/5/21

    Fingerprint

    Cells
    Tissue
    Polymers
    Cell culture
    Superconducting transition temperature

    ASJC Scopus subject areas

    • Engineering(all)

    Cite this

    Tsuda, Y., Kikuchi, A., Nakao, A., Yamato, M., Sakurai, Y., Umezu, M., & Okano, T. (2004). Increased cell functionalities with patterned co-cultures utilizing dual thermo-responsive polymer grafted surfaces. In Transactions - 7th World Biomaterials Congress (pp. 246)

    Increased cell functionalities with patterned co-cultures utilizing dual thermo-responsive polymer grafted surfaces. / Tsuda, Y.; Kikuchi, A.; Nakao, A.; Yamato, M.; Sakurai, Y.; Umezu, Mitsuo; Okano, T.

    Transactions - 7th World Biomaterials Congress. 2004. p. 246.

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Tsuda, Y, Kikuchi, A, Nakao, A, Yamato, M, Sakurai, Y, Umezu, M & Okano, T 2004, Increased cell functionalities with patterned co-cultures utilizing dual thermo-responsive polymer grafted surfaces. in Transactions - 7th World Biomaterials Congress. pp. 246, Transactions - 7th World Biomaterials Congress, Sydney, 04/5/17.
    Tsuda Y, Kikuchi A, Nakao A, Yamato M, Sakurai Y, Umezu M et al. Increased cell functionalities with patterned co-cultures utilizing dual thermo-responsive polymer grafted surfaces. In Transactions - 7th World Biomaterials Congress. 2004. p. 246
    Tsuda, Y. ; Kikuchi, A. ; Nakao, A. ; Yamato, M. ; Sakurai, Y. ; Umezu, Mitsuo ; Okano, T. / Increased cell functionalities with patterned co-cultures utilizing dual thermo-responsive polymer grafted surfaces. Transactions - 7th World Biomaterials Congress. 2004. pp. 246
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    AU - Okano, T.

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