TY - JOUR
T1 - Increases of calcium, phosphorus, and magnesium in both the right and left fibrous trigones of human heart with aging
AU - Tohno, Setsuko
AU - Azuma, Cho
AU - Tohno, Yoshiyuki
AU - Moriwake, Yumi
AU - Izu, Atsuko
AU - Kumai, Tsukasa
AU - Minami, Takeshi
N1 - Funding Information:
Acknowledgment Portions of this work were supported by a Grant-in-Aid for Scientific Research no. 17200032 from Japan Society for the Promotion of Science.
PY - 2007/11
Y1 - 2007/11
N2 - To elucidate compositional changes of the cardiac skeleton with aging, the authors investigated age-related changes of elements in both the right and left fibrous trigones of human heart by inductively coupled plasma atomic emission spectrometry (ICP-AES). After ordinary dissection by medical students was finished, hearts were resected from the subjects and both the right and left fibrous trigones were removed from the hearts. The subjects consisted of 10 men and 13 women, ranging in age from 62 to 99 years. The element content was determined by ICP-AES. The Ca, P, and Mg content began to increase in the seventies in both the right and left fibrous trigones, and increased markedly in the eighties. Regarding the relationships among element contents, extremely significant direct correlations were found among the contents of Ca, P, and Mg in both the right and left fibrous trigones.
AB - To elucidate compositional changes of the cardiac skeleton with aging, the authors investigated age-related changes of elements in both the right and left fibrous trigones of human heart by inductively coupled plasma atomic emission spectrometry (ICP-AES). After ordinary dissection by medical students was finished, hearts were resected from the subjects and both the right and left fibrous trigones were removed from the hearts. The subjects consisted of 10 men and 13 women, ranging in age from 62 to 99 years. The element content was determined by ICP-AES. The Ca, P, and Mg content began to increase in the seventies in both the right and left fibrous trigones, and increased markedly in the eighties. Regarding the relationships among element contents, extremely significant direct correlations were found among the contents of Ca, P, and Mg in both the right and left fibrous trigones.
KW - Aging
KW - Calcium
KW - Cardiac skeleton
KW - Left fibrous trigone
KW - Magnesium
KW - Phosphorus
KW - Right fibrous trigone
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U2 - 10.1007/s12011-007-0053-5
DO - 10.1007/s12011-007-0053-5
M3 - Article
C2 - 17916934
AN - SCOPUS:35348824929
SN - 0163-4984
VL - 119
SP - 111
EP - 119
JO - Biological Trace Element Research
JF - Biological Trace Element Research
IS - 2
ER -
