Influence of cardiorespiratory fitness and drinking habits on total cancer mortality: A cohort study of Japanese man

Munehiro Matsushita, Motohiko Miyachi, Ryoko Kawakami, Takashi Okamoto, Koji Tsukamoto, Yoshio Nakata, Takashi Arao, Susumu Sawada

Research output: Contribution to journalArticle

Abstract

Several studies have shown that low cardiorespiratory fitness (CRF) or heavy alcohol consumption is risks of total or certain types of cancer death. However, the combined influence of CRF and drinking habits on total cancer mortality is not clear. The purpose of this study was to investigate the joint effect of CRF and drinking habits on total cancer mortality among Japanese men. We evaluated the CRF and drinking habits on risk of total cancer mortality in 8,760 Japanese men (age: 19-59 yr) who were given a submaximal exercise test, a medical examination test, and questionnaires on their health habits. CRF was measured using a cycle ergometer test, and the men were classified into two categories by CRF levels based on the reference value of CRF (R-CRF) in "Physical Activity Reference for Health Promotion 2013" (Under R-CRF and Over R-CRF). Also, the men were assigned to Non Drinking, Moderate Drinking, and Heavy Drinking categories. There were 178 cancer deaths during the 20-yr follow-up period. Relative risk and 95% confidence intervals for total cancer mortality were obtained using the Cox proportional hazards model while adjusting for age, body mass index, systolic blood pressure, and smoking habits. Using the Under R-CRF & Heavy Drinking group as reference, the relative risk and 95% confidence intervals were 0.37 (0.16-0.85) for the Over R-CRF & Non Drinking group. This result suggests that Japanese male with a high CRF and a low drinking habit have a lower risk of total cancer mortality.

Original languageEnglish
Pages (from-to)375-381
Number of pages7
JournalJapanese Journal of Physical Fitness and Sports Medicine
Volume62
Issue number5
DOIs
Publication statusPublished - 2013

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Keywords

  • Alcohol drinking
  • Cohort study
  • Neoplasms
  • Physical fitness
  • Respiratory function tests

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

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