Influence of conduit angles on hemodynamics of modified Blalock-Taussig shunt: Computational analysis of patient-specific virtual procedures

Jinlong Liu, Qi Sun, Mitsuo Umezu, Yi Qian, Haifa Hong, Zhou Du, Qian Wang, Yanjun Sun, Jinfen Liu

    Research output: Chapter in Book/Report/Conference proceedingChapter

    4 Citations (Scopus)

    Abstract

    Currently, the modified Blalock-Taussig (mB-T) shunt is the most preferred surgery served as the first step of the staged procedures in the treatment of cyanotic congenital heart defect. A Gore-Tex conduit is used to surgically connect the systemic and pulmonary circulations. In the present study, we report on three-dimensional (3D) hemodynamic analysis of the effects of conduit anastomosis angles on hemodynamics of the mB-T shunt. We constructed a patient-specific 3D model after the mB-T shunt based on medical images and employed computer-aided design to reconstruct two new models with different anastomosis angles. The local pressure, blood flow distribution and wall shear stress were calculated. The results suggest the scheme of vertical anastomosis angle of the conduit on the pulmonary artery can increase the blood flow distribution from systemic circulation to two lungs and blood flows more smoothly in the conduit. The results are well congruent with our clinical experience. This indicates the numerical methods may be applied to investigate hemodynamics of the mB-T shunt for different surgical schemes.

    Original languageEnglish
    Title of host publicationCommunications in Computer and Information Science
    PublisherSpringer Verlag
    Pages62-71
    Number of pages10
    Volume461
    ISBN (Print)9783662452820
    Publication statusPublished - 2014

    Publication series

    NameCommunications in Computer and Information Science
    Volume461
    ISSN (Print)18650929

    Fingerprint

    Hemodynamics
    Blood
    Blood pressure
    Surgery
    Shear stress
    Numerical methods
    Computer aided design
    Defects

    Keywords

    • Computational fluid dynamics
    • Computer-aided Design
    • Congenital heart defect
    • Hemodynamics
    • Modified Blalock-Taussig shunt

    ASJC Scopus subject areas

    • Computer Science(all)

    Cite this

    Liu, J., Sun, Q., Umezu, M., Qian, Y., Hong, H., Du, Z., ... Liu, J. (2014). Influence of conduit angles on hemodynamics of modified Blalock-Taussig shunt: Computational analysis of patient-specific virtual procedures. In Communications in Computer and Information Science (Vol. 461, pp. 62-71). (Communications in Computer and Information Science; Vol. 461). Springer Verlag.

    Influence of conduit angles on hemodynamics of modified Blalock-Taussig shunt : Computational analysis of patient-specific virtual procedures. / Liu, Jinlong; Sun, Qi; Umezu, Mitsuo; Qian, Yi; Hong, Haifa; Du, Zhou; Wang, Qian; Sun, Yanjun; Liu, Jinfen.

    Communications in Computer and Information Science. Vol. 461 Springer Verlag, 2014. p. 62-71 (Communications in Computer and Information Science; Vol. 461).

    Research output: Chapter in Book/Report/Conference proceedingChapter

    Liu, J, Sun, Q, Umezu, M, Qian, Y, Hong, H, Du, Z, Wang, Q, Sun, Y & Liu, J 2014, Influence of conduit angles on hemodynamics of modified Blalock-Taussig shunt: Computational analysis of patient-specific virtual procedures. in Communications in Computer and Information Science. vol. 461, Communications in Computer and Information Science, vol. 461, Springer Verlag, pp. 62-71.
    Liu J, Sun Q, Umezu M, Qian Y, Hong H, Du Z et al. Influence of conduit angles on hemodynamics of modified Blalock-Taussig shunt: Computational analysis of patient-specific virtual procedures. In Communications in Computer and Information Science. Vol. 461. Springer Verlag. 2014. p. 62-71. (Communications in Computer and Information Science).
    Liu, Jinlong ; Sun, Qi ; Umezu, Mitsuo ; Qian, Yi ; Hong, Haifa ; Du, Zhou ; Wang, Qian ; Sun, Yanjun ; Liu, Jinfen. / Influence of conduit angles on hemodynamics of modified Blalock-Taussig shunt : Computational analysis of patient-specific virtual procedures. Communications in Computer and Information Science. Vol. 461 Springer Verlag, 2014. pp. 62-71 (Communications in Computer and Information Science).
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    AU - Qian, Yi

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    AU - Wang, Qian

    AU - Sun, Yanjun

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    AB - Currently, the modified Blalock-Taussig (mB-T) shunt is the most preferred surgery served as the first step of the staged procedures in the treatment of cyanotic congenital heart defect. A Gore-Tex conduit is used to surgically connect the systemic and pulmonary circulations. In the present study, we report on three-dimensional (3D) hemodynamic analysis of the effects of conduit anastomosis angles on hemodynamics of the mB-T shunt. We constructed a patient-specific 3D model after the mB-T shunt based on medical images and employed computer-aided design to reconstruct two new models with different anastomosis angles. The local pressure, blood flow distribution and wall shear stress were calculated. The results suggest the scheme of vertical anastomosis angle of the conduit on the pulmonary artery can increase the blood flow distribution from systemic circulation to two lungs and blood flows more smoothly in the conduit. The results are well congruent with our clinical experience. This indicates the numerical methods may be applied to investigate hemodynamics of the mB-T shunt for different surgical schemes.

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