Influence of conduit angles on hemodynamics of modified Blalock-Taussig shunt: Computational analysis of patient-specific virtual procedures

Jinlong Liu, Qi Sun, Mitsuo Umezu, Yi Qian, Haifa Hong, Zhou Du, Qian Wang, Yanjun Sun, Jinfen Liu

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Citations (Scopus)

Abstract

Currently, the modified Blalock-Taussig (mB-T) shunt is the most preferred surgery served as the first step of the staged procedures in the treatment of cyanotic congenital heart defect. A Gore-Tex conduit is used to surgically connect the systemic and pulmonary circulations. In the present study, we report on three-dimensional (3D) hemodynamic analysis of the effects of conduit anastomosis angles on hemodynamics of the mB-T shunt. We constructed a patient-specific 3D model after the mB-T shunt based on medical images and employed computer-aided design to reconstruct two new models with different anastomosis angles. The local pressure, blood flow distribution and wall shear stress were calculated. The results suggest the scheme of vertical anastomosis angle of the conduit on the pulmonary artery can increase the blood flow distribution from systemic circulation to two lungs and blood flows more smoothly in the conduit. The results are well congruent with our clinical experience. This indicates the numerical methods may be applied to investigate hemodynamics of the mB-T shunt for different surgical schemes.

Original languageEnglish
Title of host publicationLife System Modeling and Simulation - International Conference on Life System Modeling and Simulation, LSMS 2014 and International Conference on Intelligent Computing for Sustainable Energy and Environment, ICSEE 2014, Proceedings
EditorsHuiyu Zhou, Shiwei Ma, Li Jia, Xin Li, Ling Wang, Xin Sun
PublisherSpringer Verlag
Pages62-71
Number of pages10
ISBN (Electronic)9783662452820
Publication statusPublished - 2014 Jan 1

Publication series

NameCommunications in Computer and Information Science
Volume461
ISSN (Print)1865-0929

Keywords

  • Computational fluid dynamics
  • Computer-aided Design
  • Congenital heart defect
  • Hemodynamics
  • Modified Blalock-Taussig shunt

ASJC Scopus subject areas

  • Computer Science(all)
  • Mathematics(all)

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    Liu, J., Sun, Q., Umezu, M., Qian, Y., Hong, H., Du, Z., Wang, Q., Sun, Y., & Liu, J. (2014). Influence of conduit angles on hemodynamics of modified Blalock-Taussig shunt: Computational analysis of patient-specific virtual procedures. In H. Zhou, S. Ma, L. Jia, X. Li, L. Wang, & X. Sun (Eds.), Life System Modeling and Simulation - International Conference on Life System Modeling and Simulation, LSMS 2014 and International Conference on Intelligent Computing for Sustainable Energy and Environment, ICSEE 2014, Proceedings (pp. 62-71). (Communications in Computer and Information Science; Vol. 461). Springer Verlag.