Influence of peripheral hydrogen bonding on the mechanical properties of photo-cross-linked star-shaped poly(D,L-lactide) networks

Afia S. Karikari, Wesleigh F. Edwards, Jeffrey B. Mecham, Timothy Edward Long

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

Four-arm, star-shaped poly(D,L-lactide) (PDLLA) oligomers of controlled molar mass and narrow molar mass distribution were successfully synthesized by use of an ethoxylated pentaerythritol initiator. Derivatization of the terminal hydroxyl groups with either methacrylic anhydride (MAAH) or 2-isocyanatoethyl methacrylate (IEM) to yield PDLLA-M (M = methacrylate end group) and PDLLA-UM (UM = urethane methacrylate end group), respectively, was monitored by in situ Fourier transform infrared (FTIR) spectroscopy. Photo-cross-linking of the functional oligomers yielded networks with high gel contents (>95%). The glass transition temperature (Tg) of these networks was strongly dependent on prepolymer molar mass, and networks based on low molar mass precursors were more rigid than the networks obtained from higher molar mass oligomers. The tensile strength (TS) and Young's modulus of the PDLLA-M samples, approximately 7 and 17 MPa, respectively, were significantly lower than the values of 19 MPa (TS) and 113-354 MPa (Young's modulus) for the PDLLA-UM samples. The introduction of terminal hydrogen-bonding sites that were adjacent to the photo-cross-linking site resulted in higher performance poly(lactide)-based bioadhesives.

Original languageEnglish
Pages (from-to)2866-2874
Number of pages9
JournalBiomacromolecules
Volume6
Issue number5
DOIs
Publication statusPublished - 2005 Sep 1
Externally publishedYes

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Molar mass
Stars
Hydrogen bonds
Mechanical properties
Oligomers
Methacrylates
Tensile strength
Elastic moduli
Anhydrides
Urethane
Fourier transform infrared spectroscopy
Hydroxyl Radical
Gels
poly(lactide)

ASJC Scopus subject areas

  • Bioengineering
  • Biomaterials
  • Polymers and Plastics
  • Materials Chemistry

Cite this

Influence of peripheral hydrogen bonding on the mechanical properties of photo-cross-linked star-shaped poly(D,L-lactide) networks. / Karikari, Afia S.; Edwards, Wesleigh F.; Mecham, Jeffrey B.; Long, Timothy Edward.

In: Biomacromolecules, Vol. 6, No. 5, 01.09.2005, p. 2866-2874.

Research output: Contribution to journalArticle

Karikari, Afia S. ; Edwards, Wesleigh F. ; Mecham, Jeffrey B. ; Long, Timothy Edward. / Influence of peripheral hydrogen bonding on the mechanical properties of photo-cross-linked star-shaped poly(D,L-lactide) networks. In: Biomacromolecules. 2005 ; Vol. 6, No. 5. pp. 2866-2874.
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