Influence of wall thickness on fluid-structure interaction computations of cerebral aneurysms

Ryo Torii, Marie Oshima, Toshio Kobayashi, Kiyoshi Takagi, Tayfun E. Tezduyar

Research output: Contribution to journalArticle

73 Citations (Scopus)

Abstract

Fluid-structure interaction (FSI) analyses of cerebral aneurysm using patient-specific geometry with uniform and pathological aneurysmal wall thickness models are carried out. The objective is to assess the influence of the wall thickness on the FSI and hemodynamics in aneurysms. Two aneurysm models that were reconstructured based on CT images are used. The arterial wall thickness is set to 0.3mm for the non-aneurysmal artery and to 0.05mm for the aneurysmal wall based on experimental findings. Another set of aneurysm models with a uniform wall thickness of 0.3mm for the entire model is used for comparison. The FSI simulations are carried out using the deforming-spatial-domain/stabilized space-time method with physiological inflow and pressure profiles. Computations with different aneurysmal wall thicknesses depict considerable differences in displacement, flow velocity and wall shear stress (WSS). The wall displacement for the pathological wall model is 61% larger than that of the uniform wall model. Consequently, the flow velocities in the aneurysm with the pathological wall model are lower, and that results in a 51% reduction in WSS on the aneurismal wall. Because low WSS on the aneurymal wall is linked to growth and rupture risk of aneurysm, the results suggest that using uniform wall thickness for the aneurysmal wall could underestimate risk in aneurysms.

Original languageEnglish
Pages (from-to)336-347
Number of pages12
JournalInternational Journal for Numerical Methods in Biomedical Engineering
Volume26
Issue number3-4
DOIs
Publication statusPublished - 2010 Mar
Externally publishedYes

Fingerprint

Cerebral Aneurysm
Fluid structure interaction
Intracranial Aneurysm
Aneurysm
Fluid
Wall Shear Stress
Interaction
Shear stress
Flow velocity
Model
CT Image
Hemodynamics
Rupture
Arteries
Influence
Pressure
Space-time
Entire
Growth
Geometry

Keywords

  • Cerebral aneurysm
  • Fluid-structure interaction
  • Patient-Specific modeling
  • Wall thickness

ASJC Scopus subject areas

  • Software
  • Modelling and Simulation
  • Biomedical Engineering
  • Molecular Biology
  • Computational Theory and Mathematics
  • Applied Mathematics

Cite this

Influence of wall thickness on fluid-structure interaction computations of cerebral aneurysms. / Torii, Ryo; Oshima, Marie; Kobayashi, Toshio; Takagi, Kiyoshi; Tezduyar, Tayfun E.

In: International Journal for Numerical Methods in Biomedical Engineering, Vol. 26, No. 3-4, 03.2010, p. 336-347.

Research output: Contribution to journalArticle

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