Influencing factors in image-based fluid-structure interaction computation of cerebral aneurysms

Ryo Torii, Marie Oshima, Toshio Kobayashi, Kiyoshi Takagi, Tayfun E. Tezduyar

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

We review and summarize our research activities in fluid-structure interaction (FSI) analysis of cerebral aneurysms using anatomically realistic geometry models based on medical images. Emphasis is placed on influencing factors in computational FSI, and their role and clinical implications are discussed in terms of the wall shear stress (WSS). The key factors are: (1) arterial and aneurysm geometries, (2) wall structure modeling, (3) blood pressure, (4) outflow conditions and (5) inflow conditions. Among these, we find the impact of the arterial and aneurysm geometries to be the most significant. Blood pressure also has a significant impact on the WSS distribution; a hypothetical hypertensive blood pressure condition could help estimate the rupture risk for an aneurysm. We find the other three factors to be minor compared with the arterial and aneurysm geometries and blood pressure, although the level of influence could be unique to the middle cerebral artery aneurysms that we have been focusing on in our studies.

Original languageEnglish
Pages (from-to)324-340
Number of pages17
JournalInternational Journal for Numerical Methods in Fluids
Volume65
Issue number1-3
DOIs
Publication statusPublished - 2011 Jan
Externally publishedYes

Fingerprint

Cerebral Aneurysm
Aneurysm
Fluid structure interaction
Blood pressure
Blood Pressure
Fluid
Geometry
Interaction
Wall Shear Stress
Shear stress
Rupture
Stress concentration
Stress Distribution
Arteries
Medical Image
Minor
Model-based
Modeling
Estimate

Keywords

  • Cerebral aneurysm
  • Fluid-structure interaction
  • Image-based modeling
  • Middle cerebral artery
  • Space-time method

ASJC Scopus subject areas

  • Computational Mechanics
  • Mechanics of Materials
  • Mechanical Engineering
  • Computer Science Applications
  • Applied Mathematics

Cite this

Influencing factors in image-based fluid-structure interaction computation of cerebral aneurysms. / Torii, Ryo; Oshima, Marie; Kobayashi, Toshio; Takagi, Kiyoshi; Tezduyar, Tayfun E.

In: International Journal for Numerical Methods in Fluids, Vol. 65, No. 1-3, 01.2011, p. 324-340.

Research output: Contribution to journalArticle

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