Inhibition by beta-carotene - rich algae Dunaliella of spontaneous mammary tumourigenesis in mice

H. Nagasawa, R. Konishi, N. Sensui, K. Yamamoto, A. Ben-Amotz

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Effects of beta-carotene - rich algae Dunaliella on spontaneous mammary tumourigenesis were studied in SHN mice. In both breeder and virgin mice, mammary tumourigenesis was significantly inhibited in the experimental groups fed diets supplemented with spray dried powder of D. bardawil and oily solution of D. salina Teod. extract compared with the control. There was little difference between the experimental and the control groups in plasma prolactin level, endocrine organ weights and pattern of oestrous cycles. Moreover, mammary gland susceptibility to mammotrophic hormones was affected little by Dunaliella. These results suggest that the inhibition by Dunaliella of spontaneous mammary tumourigenesis of mice may not be through their modulation of endocrine systems.

Original languageEnglish
Pages (from-to)71-76
Number of pages6
JournalAnticancer Research
Volume9
Issue number1
Publication statusPublished - 1989
Externally publishedYes

Fingerprint

beta Carotene
Breast
Endocrine System
Organ Size
Human Mammary Glands
Prolactin
Powders
Hormones
Diet
Control Groups

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Nagasawa, H., Konishi, R., Sensui, N., Yamamoto, K., & Ben-Amotz, A. (1989). Inhibition by beta-carotene - rich algae Dunaliella of spontaneous mammary tumourigenesis in mice. Anticancer Research, 9(1), 71-76.

Inhibition by beta-carotene - rich algae Dunaliella of spontaneous mammary tumourigenesis in mice. / Nagasawa, H.; Konishi, R.; Sensui, N.; Yamamoto, K.; Ben-Amotz, A.

In: Anticancer Research, Vol. 9, No. 1, 1989, p. 71-76.

Research output: Contribution to journalArticle

Nagasawa, H, Konishi, R, Sensui, N, Yamamoto, K & Ben-Amotz, A 1989, 'Inhibition by beta-carotene - rich algae Dunaliella of spontaneous mammary tumourigenesis in mice', Anticancer Research, vol. 9, no. 1, pp. 71-76.
Nagasawa H, Konishi R, Sensui N, Yamamoto K, Ben-Amotz A. Inhibition by beta-carotene - rich algae Dunaliella of spontaneous mammary tumourigenesis in mice. Anticancer Research. 1989;9(1):71-76.
Nagasawa, H. ; Konishi, R. ; Sensui, N. ; Yamamoto, K. ; Ben-Amotz, A. / Inhibition by beta-carotene - rich algae Dunaliella of spontaneous mammary tumourigenesis in mice. In: Anticancer Research. 1989 ; Vol. 9, No. 1. pp. 71-76.
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