Inhibition of ovulation by the antiserum to cyclooxygenase and immunocytochemical study of cyclooxygenase in the ovarian follicles

H. Fukuoka, K. Satoh, S. Sakamoto, H. Tsuchida

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It was demonstrated that the intravenous administration of the rabbit antiserum to prostaglandin(PG) synthetase (cyclooxygenase: COase) to immature superovulated rats resulted in the inhibition of both ovulation and PG production in the follicles. The intracellular localization of the administered antiserum in the follicular cells was investigated immunocytochemically by light and electron microscopy.

Original languageEnglish
Pages (from-to)205-206
Number of pages2
JournalAdvances in the Biosciences
Issue numberC
Publication statusPublished - 1982
Externally publishedYes



  • Antiserum to cyclooxygenase
  • localization of cyclooxygenase
  • ovulation
  • prostaglandin

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