Initial sequencing and analysis of the human genome

Eric S. Lander, Lauren M. Linton, Bruce Birren, Chad Nusbaum, Michael C. Zody, Jennifer Baldwin, Keri Devon, Ken Dewar, Michael Doyle, William Fitzhugh, Roel Funke, Diane Gage, Katrina Harris, Andrew Heaford, John Howland, Lisa Kann, Jessica Lehoczky, Rosie Levine, Paul McEwan, Kevin McKernan & 229 others James Meldrim, Jill P. Mesirov, Cher Miranda, William Morris, Jerome Naylor, Christina Raymond, Mark Rosetti, Ralph Santos, Andrew Sheridan, Carrie Sougnez, Nicole Stange-Thomann, Nikola Stojanovic, Aravind Subramanian, Dudley Wyman, Jane Rogers, John Sulston, Rachael Ainscough, Stephan Beck, David Bentley, John Burton, Christopher Clee, Nigel Carter, Alan Coulson, Rebecca Deadman, Panos Deloukas, Andrew Dunham, Ian Dunham, Richard Durbin, Lisa French, Darren Grafham, Simon Gregory, Tim Hubbard, Sean Humphray, Adrienne Hunt, Matthew Jones, Christine Lloyd, Amanda McMurray, Lucy Matthews, Simon Mercer, Sarah Milne, James C. Mullikin, Andrew Mungall, Robert Plumb, Mark Ross, Ratna Shownkeen, Sarah Sims, Robert H. Waterston, Richard K. Wilson, Ladeana W. Hillier, John D. McPherson, Marco A. Marra, Elaine R. Mardis, Lucinda A. Fulton, Asif T. Chinwalla, Kymberlie H. Pepin, Warren R. Gish, Stephanie L. Chissoe, Michael C. Wendl, Kim D. Delehaunty, Tracie L. Miner, Andrew Delehaunty, Jason B. Kramer, Lisa L. Cook, Robert S. Fulton, Douglas L. Johnson, Patrick J. Minx, Sandra W. Clifton, Trevor Hawkins, Elbert Branscomb, Paul Predki, Paul Richardson, Sarah Wenning, Tom Slezak, Norman Doggett, Jan Fang Cheng, Anne Olsen, Susan Lucas, Christopher Elkin, Edward Uberbacher, Marvin Frazier, Richard A. Gibbs, Donna M. Muzny, Steven E. Scherer, John B. Bouck, Erica J. Sodergren, Kim C. Worley, Catherine M. Rives, James H. Gorrell, Michael L. Metzker, Susan L. Naylor, Raju S. Kucherlapati, David L. Nelson, George M. Weinstock, Yoshiyuki Sakaki, Asao Fujiyama, Masahira Hattori, Tetsushi Yada, Atsushi Toyoda, Takehiko Itoh, Chiharu Kawagoe, Hidemi Watanabe, Yasushi Totoki, Todd Taylor, Jean Weissenbach, Roland Heilig, William Saurin, Francois Artiguenave, Philippe Brottier, Thomas Bruls, Eric Pelletier, Catherine Robert, Patrick Wincker, André Rosenthal, Matthias Platzer, Gerald Nyakatura, Stefan Taudien, Andreas Rump, Douglas R. Smith, Lynn Doucette-Stamm, Marc Rubenfield, Keith Weinstock, Mei Lee Hong, Joann Dubois, Huanming Yang, Jun Yu, Jian Wang, Guyang Huang, Jun Gu, Leroy Hood, Lee Rowen, Anup Madan, Shizen Qin, Ronald W. Davis, Nancy A. Federspiel, A. Pia Abola, Michael J. Proctor, Bruce A. Roe, Feng Chen, Huaqin Pan, Juliane Ramser, Hans Lehrach, Richard Reinhardt, W. Richard McCombie, Melissa De La Bastide, Neilay Dedhia, Helmut Blöcker, Klaus Hornischer, Gabriele Nordsiek, Richa Agarwala, L. Aravind, Jeffrey A. Bailey, Alex Bateman, Serafim Batzoglou, Ewan Birney, Peer Bork, Daniel G. Brown, Christopher B. Burge, Lorenzo Cerutti, Hsiu Chuan Chen, Deanna Church, Michele Clamp, Richard R. Copley, Tobias Doerks, Sean R. Eddy, Evan E. Eichler, Terrence S. Furey, James Galagan, James G R Gilbert, Cyrus Harmon, Yoshihide Hayashizaki, David Haussler, Henning Hermjakob, Karsten Hokamp, Wonhee Jang, L. Steven Johnson, Thomas A. Jones, Simon Kasif, Arek Kaspryzk, Scot Kennedy, W. James Kent, Paul Kitts, Eugene V. Koonin, Ian Korf, David Kulp, Doron Lancet, Todd M. Lowe, Aoife McLysaght, Tarjei Mikkelsen, John V. Moran, Nicola Mulder, Victor J. Pollara, Chris P. Ponting, Greg Schuler, Jörg Schultz, Guy Slater, Arian F A Smit, Elia Stupka, Joseph Szustakowki, Danielle Thierry-Mieg, Jean Thierry-Mieg, Lukas Wagner, John Wallis, Raymond Wheeler, Alan Williams, Yuri I. Wolf, Kenneth H. Wolfe, Shiaw Pyng Yang, Ru Fang Yeh, Francis Collins, Mark S. Guyer, Jane Peterson, Adam Felsenfeld, Kris A. Wetterstrand, Richard M. Myers, Jeremy Schmutz, Mark Dickson, Jane Grimwood, David R. Cox, Maynard V. Olson, Rajinder Kaul, Christopher Raymond, Nobuyoshi Shimizu, Kazuhiko Kawasaki, Shinsei Minoshima, Glen A. Evans, Maria Athanasiou, Roger Schultz, Aristides Patrinos, Michael J. Morgan

Research output: Contribution to journalArticle

15110 Citations (Scopus)

Abstract

The human genome holds an extraordinary trove of information about human development, physiology, medicine and evolution. Here we report the results of an international collaboration to produce and make freely available a draft sequence of the human genome. We also present an initial analysis of the data, describing some of the insights that can be gleaned from the sequence.

Original languageEnglish
Pages (from-to)860-921
Number of pages62
JournalNature
Volume409
Issue number6822
DOIs
Publication statusPublished - 2001 Feb 15
Externally publishedYes

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Human Genome
Human Development
Medicine

ASJC Scopus subject areas

  • General

Cite this

Lander, E. S., Linton, L. M., Birren, B., Nusbaum, C., Zody, M. C., Baldwin, J., ... Morgan, M. J. (2001). Initial sequencing and analysis of the human genome. Nature, 409(6822), 860-921. https://doi.org/10.1038/35057062

Initial sequencing and analysis of the human genome. / Lander, Eric S.; Linton, Lauren M.; Birren, Bruce; Nusbaum, Chad; Zody, Michael C.; Baldwin, Jennifer; Devon, Keri; Dewar, Ken; Doyle, Michael; Fitzhugh, William; Funke, Roel; Gage, Diane; Harris, Katrina; Heaford, Andrew; Howland, John; Kann, Lisa; Lehoczky, Jessica; Levine, Rosie; McEwan, Paul; McKernan, Kevin; Meldrim, James; Mesirov, Jill P.; Miranda, Cher; Morris, William; Naylor, Jerome; Raymond, Christina; Rosetti, Mark; Santos, Ralph; Sheridan, Andrew; Sougnez, Carrie; Stange-Thomann, Nicole; Stojanovic, Nikola; Subramanian, Aravind; Wyman, Dudley; Rogers, Jane; Sulston, John; Ainscough, Rachael; Beck, Stephan; Bentley, David; Burton, John; Clee, Christopher; Carter, Nigel; Coulson, Alan; Deadman, Rebecca; Deloukas, Panos; Dunham, Andrew; Dunham, Ian; Durbin, Richard; French, Lisa; Grafham, Darren; Gregory, Simon; Hubbard, Tim; Humphray, Sean; Hunt, Adrienne; Jones, Matthew; Lloyd, Christine; McMurray, Amanda; Matthews, Lucy; Mercer, Simon; Milne, Sarah; Mullikin, James C.; Mungall, Andrew; Plumb, Robert; Ross, Mark; Shownkeen, Ratna; Sims, Sarah; Waterston, Robert H.; Wilson, Richard K.; Hillier, Ladeana W.; McPherson, John D.; Marra, Marco A.; Mardis, Elaine R.; Fulton, Lucinda A.; Chinwalla, Asif T.; Pepin, Kymberlie H.; Gish, Warren R.; Chissoe, Stephanie L.; Wendl, Michael C.; Delehaunty, Kim D.; Miner, Tracie L.; Delehaunty, Andrew; Kramer, Jason B.; Cook, Lisa L.; Fulton, Robert S.; Johnson, Douglas L.; Minx, Patrick J.; Clifton, Sandra W.; Hawkins, Trevor; Branscomb, Elbert; Predki, Paul; Richardson, Paul; Wenning, Sarah; Slezak, Tom; Doggett, Norman; Cheng, Jan Fang; Olsen, Anne; Lucas, Susan; Elkin, Christopher; Uberbacher, Edward; Frazier, Marvin; Gibbs, Richard A.; Muzny, Donna M.; Scherer, Steven E.; Bouck, John B.; Sodergren, Erica J.; Worley, Kim C.; Rives, Catherine M.; Gorrell, James H.; Metzker, Michael L.; Naylor, Susan L.; Kucherlapati, Raju S.; Nelson, David L.; Weinstock, George M.; Sakaki, Yoshiyuki; Fujiyama, Asao; Hattori, Masahira; Yada, Tetsushi; Toyoda, Atsushi; Itoh, Takehiko; Kawagoe, Chiharu; Watanabe, Hidemi; Totoki, Yasushi; Taylor, Todd; Weissenbach, Jean; Heilig, Roland; Saurin, William; Artiguenave, Francois; Brottier, Philippe; Bruls, Thomas; Pelletier, Eric; Robert, Catherine; Wincker, Patrick; Rosenthal, André; Platzer, Matthias; Nyakatura, Gerald; Taudien, Stefan; Rump, Andreas; Smith, Douglas R.; Doucette-Stamm, Lynn; Rubenfield, Marc; Weinstock, Keith; Hong, Mei Lee; Dubois, Joann; Yang, Huanming; Yu, Jun; Wang, Jian; Huang, Guyang; Gu, Jun; Hood, Leroy; Rowen, Lee; Madan, Anup; Qin, Shizen; Davis, Ronald W.; Federspiel, Nancy A.; Abola, A. Pia; Proctor, Michael J.; Roe, Bruce A.; Chen, Feng; Pan, Huaqin; Ramser, Juliane; Lehrach, Hans; Reinhardt, Richard; McCombie, W. Richard; De La Bastide, Melissa; Dedhia, Neilay; Blöcker, Helmut; Hornischer, Klaus; Nordsiek, Gabriele; Agarwala, Richa; Aravind, L.; Bailey, Jeffrey A.; Bateman, Alex; Batzoglou, Serafim; Birney, Ewan; Bork, Peer; Brown, Daniel G.; Burge, Christopher B.; Cerutti, Lorenzo; Chen, Hsiu Chuan; Church, Deanna; Clamp, Michele; Copley, Richard R.; Doerks, Tobias; Eddy, Sean R.; Eichler, Evan E.; Furey, Terrence S.; Galagan, James; Gilbert, James G R; Harmon, Cyrus; Hayashizaki, Yoshihide; Haussler, David; Hermjakob, Henning; Hokamp, Karsten; Jang, Wonhee; Johnson, L. Steven; Jones, Thomas A.; Kasif, Simon; Kaspryzk, Arek; Kennedy, Scot; Kent, W. James; Kitts, Paul; Koonin, Eugene V.; Korf, Ian; Kulp, David; Lancet, Doron; Lowe, Todd M.; McLysaght, Aoife; Mikkelsen, Tarjei; Moran, John V.; Mulder, Nicola; Pollara, Victor J.; Ponting, Chris P.; Schuler, Greg; Schultz, Jörg; Slater, Guy; Smit, Arian F A; Stupka, Elia; Szustakowki, Joseph; Thierry-Mieg, Danielle; Thierry-Mieg, Jean; Wagner, Lukas; Wallis, John; Wheeler, Raymond; Williams, Alan; Wolf, Yuri I.; Wolfe, Kenneth H.; Yang, Shiaw Pyng; Yeh, Ru Fang; Collins, Francis; Guyer, Mark S.; Peterson, Jane; Felsenfeld, Adam; Wetterstrand, Kris A.; Myers, Richard M.; Schmutz, Jeremy; Dickson, Mark; Grimwood, Jane; Cox, David R.; Olson, Maynard V.; Kaul, Rajinder; Raymond, Christopher; Shimizu, Nobuyoshi; Kawasaki, Kazuhiko; Minoshima, Shinsei; Evans, Glen A.; Athanasiou, Maria; Schultz, Roger; Patrinos, Aristides; Morgan, Michael J.

In: Nature, Vol. 409, No. 6822, 15.02.2001, p. 860-921.

Research output: Contribution to journalArticle

Lander, ES, Linton, LM, Birren, B, Nusbaum, C, Zody, MC, Baldwin, J, Devon, K, Dewar, K, Doyle, M, Fitzhugh, W, Funke, R, Gage, D, Harris, K, Heaford, A, Howland, J, Kann, L, Lehoczky, J, Levine, R, McEwan, P, McKernan, K, Meldrim, J, Mesirov, JP, Miranda, C, Morris, W, Naylor, J, Raymond, C, Rosetti, M, Santos, R, Sheridan, A, Sougnez, C, Stange-Thomann, N, Stojanovic, N, Subramanian, A, Wyman, D, Rogers, J, Sulston, J, Ainscough, R, Beck, S, Bentley, D, Burton, J, Clee, C, Carter, N, Coulson, A, Deadman, R, Deloukas, P, Dunham, A, Dunham, I, Durbin, R, French, L, Grafham, D, Gregory, S, Hubbard, T, Humphray, S, Hunt, A, Jones, M, Lloyd, C, McMurray, A, Matthews, L, Mercer, S, Milne, S, Mullikin, JC, Mungall, A, Plumb, R, Ross, M, Shownkeen, R, Sims, S, Waterston, RH, Wilson, RK, Hillier, LW, McPherson, JD, Marra, MA, Mardis, ER, Fulton, LA, Chinwalla, AT, Pepin, KH, Gish, WR, Chissoe, SL, Wendl, MC, Delehaunty, KD, Miner, TL, Delehaunty, A, Kramer, JB, Cook, LL, Fulton, RS, Johnson, DL, Minx, PJ, Clifton, SW, Hawkins, T, Branscomb, E, Predki, P, Richardson, P, Wenning, S, Slezak, T, Doggett, N, Cheng, JF, Olsen, A, Lucas, S, Elkin, C, Uberbacher, E, Frazier, M, Gibbs, RA, Muzny, DM, Scherer, SE, Bouck, JB, Sodergren, EJ, Worley, KC, Rives, CM, Gorrell, JH, Metzker, ML, Naylor, SL, Kucherlapati, RS, Nelson, DL, Weinstock, GM, Sakaki, Y, Fujiyama, A, Hattori, M, Yada, T, Toyoda, A, Itoh, T, Kawagoe, C, Watanabe, H, Totoki, Y, Taylor, T, Weissenbach, J, Heilig, R, Saurin, W, Artiguenave, F, Brottier, P, Bruls, T, Pelletier, E, Robert, C, Wincker, P, Rosenthal, A, Platzer, M, Nyakatura, G, Taudien, S, Rump, A, Smith, DR, Doucette-Stamm, L, Rubenfield, M, Weinstock, K, Hong, ML, Dubois, J, Yang, H, Yu, J, Wang, J, Huang, G, Gu, J, Hood, L, Rowen, L, Madan, A, Qin, S, Davis, RW, Federspiel, NA, Abola, AP, Proctor, MJ, Roe, BA, Chen, F, Pan, H, Ramser, J, Lehrach, H, Reinhardt, R, McCombie, WR, De La Bastide, M, Dedhia, N, Blöcker, H, Hornischer, K, Nordsiek, G, Agarwala, R, Aravind, L, Bailey, JA, Bateman, A, Batzoglou, S, Birney, E, Bork, P, Brown, DG, Burge, CB, Cerutti, L, Chen, HC, Church, D, Clamp, M, Copley, RR, Doerks, T, Eddy, SR, Eichler, EE, Furey, TS, Galagan, J, Gilbert, JGR, Harmon, C, Hayashizaki, Y, Haussler, D, Hermjakob, H, Hokamp, K, Jang, W, Johnson, LS, Jones, TA, Kasif, S, Kaspryzk, A, Kennedy, S, Kent, WJ, Kitts, P, Koonin, EV, Korf, I, Kulp, D, Lancet, D, Lowe, TM, McLysaght, A, Mikkelsen, T, Moran, JV, Mulder, N, Pollara, VJ, Ponting, CP, Schuler, G, Schultz, J, Slater, G, Smit, AFA, Stupka, E, Szustakowki, J, Thierry-Mieg, D, Thierry-Mieg, J, Wagner, L, Wallis, J, Wheeler, R, Williams, A, Wolf, YI, Wolfe, KH, Yang, SP, Yeh, RF, Collins, F, Guyer, MS, Peterson, J, Felsenfeld, A, Wetterstrand, KA, Myers, RM, Schmutz, J, Dickson, M, Grimwood, J, Cox, DR, Olson, MV, Kaul, R, Raymond, C, Shimizu, N, Kawasaki, K, Minoshima, S, Evans, GA, Athanasiou, M, Schultz, R, Patrinos, A & Morgan, MJ 2001, 'Initial sequencing and analysis of the human genome', Nature, vol. 409, no. 6822, pp. 860-921. https://doi.org/10.1038/35057062
Lander ES, Linton LM, Birren B, Nusbaum C, Zody MC, Baldwin J et al. Initial sequencing and analysis of the human genome. Nature. 2001 Feb 15;409(6822):860-921. https://doi.org/10.1038/35057062
Lander, Eric S. ; Linton, Lauren M. ; Birren, Bruce ; Nusbaum, Chad ; Zody, Michael C. ; Baldwin, Jennifer ; Devon, Keri ; Dewar, Ken ; Doyle, Michael ; Fitzhugh, William ; Funke, Roel ; Gage, Diane ; Harris, Katrina ; Heaford, Andrew ; Howland, John ; Kann, Lisa ; Lehoczky, Jessica ; Levine, Rosie ; McEwan, Paul ; McKernan, Kevin ; Meldrim, James ; Mesirov, Jill P. ; Miranda, Cher ; Morris, William ; Naylor, Jerome ; Raymond, Christina ; Rosetti, Mark ; Santos, Ralph ; Sheridan, Andrew ; Sougnez, Carrie ; Stange-Thomann, Nicole ; Stojanovic, Nikola ; Subramanian, Aravind ; Wyman, Dudley ; Rogers, Jane ; Sulston, John ; Ainscough, Rachael ; Beck, Stephan ; Bentley, David ; Burton, John ; Clee, Christopher ; Carter, Nigel ; Coulson, Alan ; Deadman, Rebecca ; Deloukas, Panos ; Dunham, Andrew ; Dunham, Ian ; Durbin, Richard ; French, Lisa ; Grafham, Darren ; Gregory, Simon ; Hubbard, Tim ; Humphray, Sean ; Hunt, Adrienne ; Jones, Matthew ; Lloyd, Christine ; McMurray, Amanda ; Matthews, Lucy ; Mercer, Simon ; Milne, Sarah ; Mullikin, James C. ; Mungall, Andrew ; Plumb, Robert ; Ross, Mark ; Shownkeen, Ratna ; Sims, Sarah ; Waterston, Robert H. ; Wilson, Richard K. ; Hillier, Ladeana W. ; McPherson, John D. ; Marra, Marco A. ; Mardis, Elaine R. ; Fulton, Lucinda A. ; Chinwalla, Asif T. ; Pepin, Kymberlie H. ; Gish, Warren R. ; Chissoe, Stephanie L. ; Wendl, Michael C. ; Delehaunty, Kim D. ; Miner, Tracie L. ; Delehaunty, Andrew ; Kramer, Jason B. ; Cook, Lisa L. ; Fulton, Robert S. ; Johnson, Douglas L. ; Minx, Patrick J. ; Clifton, Sandra W. ; Hawkins, Trevor ; Branscomb, Elbert ; Predki, Paul ; Richardson, Paul ; Wenning, Sarah ; Slezak, Tom ; Doggett, Norman ; Cheng, Jan Fang ; Olsen, Anne ; Lucas, Susan ; Elkin, Christopher ; Uberbacher, Edward ; Frazier, Marvin ; Gibbs, Richard A. ; Muzny, Donna M. ; Scherer, Steven E. ; Bouck, John B. ; Sodergren, Erica J. ; Worley, Kim C. ; Rives, Catherine M. ; Gorrell, James H. ; Metzker, Michael L. ; Naylor, Susan L. ; Kucherlapati, Raju S. ; Nelson, David L. ; Weinstock, George M. ; Sakaki, Yoshiyuki ; Fujiyama, Asao ; Hattori, Masahira ; Yada, Tetsushi ; Toyoda, Atsushi ; Itoh, Takehiko ; Kawagoe, Chiharu ; Watanabe, Hidemi ; Totoki, Yasushi ; Taylor, Todd ; Weissenbach, Jean ; Heilig, Roland ; Saurin, William ; Artiguenave, Francois ; Brottier, Philippe ; Bruls, Thomas ; Pelletier, Eric ; Robert, Catherine ; Wincker, Patrick ; Rosenthal, André ; Platzer, Matthias ; Nyakatura, Gerald ; Taudien, Stefan ; Rump, Andreas ; Smith, Douglas R. ; Doucette-Stamm, Lynn ; Rubenfield, Marc ; Weinstock, Keith ; Hong, Mei Lee ; Dubois, Joann ; Yang, Huanming ; Yu, Jun ; Wang, Jian ; Huang, Guyang ; Gu, Jun ; Hood, Leroy ; Rowen, Lee ; Madan, Anup ; Qin, Shizen ; Davis, Ronald W. ; Federspiel, Nancy A. ; Abola, A. Pia ; Proctor, Michael J. ; Roe, Bruce A. ; Chen, Feng ; Pan, Huaqin ; Ramser, Juliane ; Lehrach, Hans ; Reinhardt, Richard ; McCombie, W. Richard ; De La Bastide, Melissa ; Dedhia, Neilay ; Blöcker, Helmut ; Hornischer, Klaus ; Nordsiek, Gabriele ; Agarwala, Richa ; Aravind, L. ; Bailey, Jeffrey A. ; Bateman, Alex ; Batzoglou, Serafim ; Birney, Ewan ; Bork, Peer ; Brown, Daniel G. ; Burge, Christopher B. ; Cerutti, Lorenzo ; Chen, Hsiu Chuan ; Church, Deanna ; Clamp, Michele ; Copley, Richard R. ; Doerks, Tobias ; Eddy, Sean R. ; Eichler, Evan E. ; Furey, Terrence S. ; Galagan, James ; Gilbert, James G R ; Harmon, Cyrus ; Hayashizaki, Yoshihide ; Haussler, David ; Hermjakob, Henning ; Hokamp, Karsten ; Jang, Wonhee ; Johnson, L. Steven ; Jones, Thomas A. ; Kasif, Simon ; Kaspryzk, Arek ; Kennedy, Scot ; Kent, W. James ; Kitts, Paul ; Koonin, Eugene V. ; Korf, Ian ; Kulp, David ; Lancet, Doron ; Lowe, Todd M. ; McLysaght, Aoife ; Mikkelsen, Tarjei ; Moran, John V. ; Mulder, Nicola ; Pollara, Victor J. ; Ponting, Chris P. ; Schuler, Greg ; Schultz, Jörg ; Slater, Guy ; Smit, Arian F A ; Stupka, Elia ; Szustakowki, Joseph ; Thierry-Mieg, Danielle ; Thierry-Mieg, Jean ; Wagner, Lukas ; Wallis, John ; Wheeler, Raymond ; Williams, Alan ; Wolf, Yuri I. ; Wolfe, Kenneth H. ; Yang, Shiaw Pyng ; Yeh, Ru Fang ; Collins, Francis ; Guyer, Mark S. ; Peterson, Jane ; Felsenfeld, Adam ; Wetterstrand, Kris A. ; Myers, Richard M. ; Schmutz, Jeremy ; Dickson, Mark ; Grimwood, Jane ; Cox, David R. ; Olson, Maynard V. ; Kaul, Rajinder ; Raymond, Christopher ; Shimizu, Nobuyoshi ; Kawasaki, Kazuhiko ; Minoshima, Shinsei ; Evans, Glen A. ; Athanasiou, Maria ; Schultz, Roger ; Patrinos, Aristides ; Morgan, Michael J. / Initial sequencing and analysis of the human genome. In: Nature. 2001 ; Vol. 409, No. 6822. pp. 860-921.
@article{ac5b884d15134e15be39d7d6b9d8fde5,
title = "Initial sequencing and analysis of the human genome",
abstract = "The human genome holds an extraordinary trove of information about human development, physiology, medicine and evolution. Here we report the results of an international collaboration to produce and make freely available a draft sequence of the human genome. We also present an initial analysis of the data, describing some of the insights that can be gleaned from the sequence.",
author = "Lander, {Eric S.} and Linton, {Lauren M.} and Bruce Birren and Chad Nusbaum and Zody, {Michael C.} and Jennifer Baldwin and Keri Devon and Ken Dewar and Michael Doyle and William Fitzhugh and Roel Funke and Diane Gage and Katrina Harris and Andrew Heaford and John Howland and Lisa Kann and Jessica Lehoczky and Rosie Levine and Paul McEwan and Kevin McKernan and James Meldrim and Mesirov, {Jill P.} and Cher Miranda and William Morris and Jerome Naylor and Christina Raymond and Mark Rosetti and Ralph Santos and Andrew Sheridan and Carrie Sougnez and Nicole Stange-Thomann and Nikola Stojanovic and Aravind Subramanian and Dudley Wyman and Jane Rogers and John Sulston and Rachael Ainscough and Stephan Beck and David Bentley and John Burton and Christopher Clee and Nigel Carter and Alan Coulson and Rebecca Deadman and Panos Deloukas and Andrew Dunham and Ian Dunham and Richard Durbin and Lisa French and Darren Grafham and Simon Gregory and Tim Hubbard and Sean Humphray and Adrienne Hunt and Matthew Jones and Christine Lloyd and Amanda McMurray and Lucy Matthews and Simon Mercer and Sarah Milne and Mullikin, {James C.} and Andrew Mungall and Robert Plumb and Mark Ross and Ratna Shownkeen and Sarah Sims and Waterston, {Robert H.} and Wilson, {Richard K.} and Hillier, {Ladeana W.} and McPherson, {John D.} and Marra, {Marco A.} and Mardis, {Elaine R.} and Fulton, {Lucinda A.} and Chinwalla, {Asif T.} and Pepin, {Kymberlie H.} and Gish, {Warren R.} and Chissoe, {Stephanie L.} and Wendl, {Michael C.} and Delehaunty, {Kim D.} and Miner, {Tracie L.} and Andrew Delehaunty and Kramer, {Jason B.} and Cook, {Lisa L.} and Fulton, {Robert S.} and Johnson, {Douglas L.} and Minx, {Patrick J.} and Clifton, {Sandra W.} and Trevor Hawkins and Elbert Branscomb and Paul Predki and Paul Richardson and Sarah Wenning and Tom Slezak and Norman Doggett and Cheng, {Jan Fang} and Anne Olsen and Susan Lucas and Christopher Elkin and Edward Uberbacher and Marvin Frazier and Gibbs, {Richard A.} and Muzny, {Donna M.} and Scherer, {Steven E.} and Bouck, {John B.} and Sodergren, {Erica J.} and Worley, {Kim C.} and Rives, {Catherine M.} and Gorrell, {James H.} and Metzker, {Michael L.} and Naylor, {Susan L.} and Kucherlapati, {Raju S.} and Nelson, {David L.} and Weinstock, {George M.} and Yoshiyuki Sakaki and Asao Fujiyama and Masahira Hattori and Tetsushi Yada and Atsushi Toyoda and Takehiko Itoh and Chiharu Kawagoe and Hidemi Watanabe and Yasushi Totoki and Todd Taylor and Jean Weissenbach and Roland Heilig and William Saurin and Francois Artiguenave and Philippe Brottier and Thomas Bruls and Eric Pelletier and Catherine Robert and Patrick Wincker and Andr{\'e} Rosenthal and Matthias Platzer and Gerald Nyakatura and Stefan Taudien and Andreas Rump and Smith, {Douglas R.} and Lynn Doucette-Stamm and Marc Rubenfield and Keith Weinstock and Hong, {Mei Lee} and Joann Dubois and Huanming Yang and Jun Yu and Jian Wang and Guyang Huang and Jun Gu and Leroy Hood and Lee Rowen and Anup Madan and Shizen Qin and Davis, {Ronald W.} and Federspiel, {Nancy A.} and Abola, {A. Pia} and Proctor, {Michael J.} and Roe, {Bruce A.} and Feng Chen and Huaqin Pan and Juliane Ramser and Hans Lehrach and Richard Reinhardt and McCombie, {W. Richard} and {De La Bastide}, Melissa and Neilay Dedhia and Helmut Bl{\"o}cker and Klaus Hornischer and Gabriele Nordsiek and Richa Agarwala and L. Aravind and Bailey, {Jeffrey A.} and Alex Bateman and Serafim Batzoglou and Ewan Birney and Peer Bork and Brown, {Daniel G.} and Burge, {Christopher B.} and Lorenzo Cerutti and Chen, {Hsiu Chuan} and Deanna Church and Michele Clamp and Copley, {Richard R.} and Tobias Doerks and Eddy, {Sean R.} and Eichler, {Evan E.} and Furey, {Terrence S.} and James Galagan and Gilbert, {James G R} and Cyrus Harmon and Yoshihide Hayashizaki and David Haussler and Henning Hermjakob and Karsten Hokamp and Wonhee Jang and Johnson, {L. Steven} and Jones, {Thomas A.} and Simon Kasif and Arek Kaspryzk and Scot Kennedy and Kent, {W. James} and Paul Kitts and Koonin, {Eugene V.} and Ian Korf and David Kulp and Doron Lancet and Lowe, {Todd M.} and Aoife McLysaght and Tarjei Mikkelsen and Moran, {John V.} and Nicola Mulder and Pollara, {Victor J.} and Ponting, {Chris P.} and Greg Schuler and J{\"o}rg Schultz and Guy Slater and Smit, {Arian F A} and Elia Stupka and Joseph Szustakowki and Danielle Thierry-Mieg and Jean Thierry-Mieg and Lukas Wagner and John Wallis and Raymond Wheeler and Alan Williams and Wolf, {Yuri I.} and Wolfe, {Kenneth H.} and Yang, {Shiaw Pyng} and Yeh, {Ru Fang} and Francis Collins and Guyer, {Mark S.} and Jane Peterson and Adam Felsenfeld and Wetterstrand, {Kris A.} and Myers, {Richard M.} and Jeremy Schmutz and Mark Dickson and Jane Grimwood and Cox, {David R.} and Olson, {Maynard V.} and Rajinder Kaul and Christopher Raymond and Nobuyoshi Shimizu and Kazuhiko Kawasaki and Shinsei Minoshima and Evans, {Glen A.} and Maria Athanasiou and Roger Schultz and Aristides Patrinos and Morgan, {Michael J.}",
year = "2001",
month = "2",
day = "15",
doi = "10.1038/35057062",
language = "English",
volume = "409",
pages = "860--921",
journal = "Nature",
issn = "0028-0836",
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TY - JOUR

T1 - Initial sequencing and analysis of the human genome

AU - Lander, Eric S.

AU - Linton, Lauren M.

AU - Birren, Bruce

AU - Nusbaum, Chad

AU - Zody, Michael C.

AU - Baldwin, Jennifer

AU - Devon, Keri

AU - Dewar, Ken

AU - Doyle, Michael

AU - Fitzhugh, William

AU - Funke, Roel

AU - Gage, Diane

AU - Harris, Katrina

AU - Heaford, Andrew

AU - Howland, John

AU - Kann, Lisa

AU - Lehoczky, Jessica

AU - Levine, Rosie

AU - McEwan, Paul

AU - McKernan, Kevin

AU - Meldrim, James

AU - Mesirov, Jill P.

AU - Miranda, Cher

AU - Morris, William

AU - Naylor, Jerome

AU - Raymond, Christina

AU - Rosetti, Mark

AU - Santos, Ralph

AU - Sheridan, Andrew

AU - Sougnez, Carrie

AU - Stange-Thomann, Nicole

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PY - 2001/2/15

Y1 - 2001/2/15

N2 - The human genome holds an extraordinary trove of information about human development, physiology, medicine and evolution. Here we report the results of an international collaboration to produce and make freely available a draft sequence of the human genome. We also present an initial analysis of the data, describing some of the insights that can be gleaned from the sequence.

AB - The human genome holds an extraordinary trove of information about human development, physiology, medicine and evolution. Here we report the results of an international collaboration to produce and make freely available a draft sequence of the human genome. We also present an initial analysis of the data, describing some of the insights that can be gleaned from the sequence.

UR - http://www.scopus.com/inward/record.url?scp=2042437650&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=2042437650&partnerID=8YFLogxK

U2 - 10.1038/35057062

DO - 10.1038/35057062

M3 - Article

VL - 409

SP - 860

EP - 921

JO - Nature

JF - Nature

SN - 0028-0836

IS - 6822

ER -