Abstract
Flexible materials are important for the development of neural probes in recording stable signals (spikes) in vivo. Here, we present inkjet-printed, flexible neural probes for spike recording by using polymeric thin films. The neural probes were constructed from 400 nm-thick poly(d,l-lactic acid) nanofilms, inkjet-printed lines consisting of Au and poly(3,4-ethylenedioxythiophene):polystyrenesulfonate nanoinks, and fluoropolymer layers. Microelectrodes were exposed by cutting the edge with a razor. The 6 μm-thick probes were connected to the external amplifiers by gradual increase of stiffness with thickness-dependent manner. The probe was formed into a needle shape, which recorded spikes from mouse thalamus in vivo.
Original language | English |
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Pages (from-to) | 20-26 |
Number of pages | 7 |
Journal | ACS Applied Bio Materials |
Volume | 2 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2019 Jan 22 |
Keywords
- inkjet printing
- neural electrode
- optogenetics
- polymer nanofilm
- printed electronics
ASJC Scopus subject areas
- Biomaterials
- Chemistry(all)
- Biomedical Engineering
- Biochemistry, medical