Integration of a gradient elution system for pressure-driven liquid chromatography with mems fabricated efficient pillar array columns

Y. Song, M. Noguchi, K. Takatsuki, T. Sekiguchi, S. Shoji, T. Funatsu, J. Mizuno, M. Tsunoda

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

This paper reports a gradient elution system for pressure-driven liquid chromatography (LC) on a chip. We have already reported the microfabrication of efficient pillar array columns with low dispersion turns. For faster and more efficient analysis, we fabricated a gradient elution system with a cross-Tesla mixer for the effective mixing of two solutions on a chip with a separation channel of pillar array columns and a sample injection channel. The results of the separation of two dyes under gradient elution conditions actually showed that the developed chip performed better, faster and more efficiently.

Original languageEnglish
Title of host publication15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Pages635-637
Number of pages3
Publication statusPublished - 2011 Dec 1
Event15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011 - Seattle, WA, United States
Duration: 2011 Oct 22011 Oct 6

Publication series

Name15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
Volume1

Conference

Conference15th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2011, MicroTAS 2011
CountryUnited States
CitySeattle, WA
Period11/10/211/10/6

Keywords

  • Cross-tesla mixer
  • Fluorescence
  • Reversed-phase
  • Separation

ASJC Scopus subject areas

  • Control and Systems Engineering

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