Interactions of functionalized polymeric liposomes having a porphinato-iron complex with some biological cells and components in vitro

Etsuo Hasegawa, Kiyoshi Eshima, Yoh Ichi Matsushita, Hiroyuki Nishide, Eishun Tsuchida

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The hemocompatibility of functionalized polymeric liposome particles (diameter: 20-32 nm), which have a synthetic porphinato-iron complex in their polymerized bilayers and can carry oxygen, was studied in vitro. The ultramicroparticles did not induce hemolysis, platelet aggregation and plasma coagulation directly and were stable against hydrolysis by phospholipases A2 and D.

Original languageEnglish
Pages (from-to)235-242
Number of pages8
JournalBBA - Biomembranes
Volume862
Issue number2
DOIs
Publication statusPublished - 1986 Nov 17

Keywords

  • Hemocompatibility
  • Hemolysis
  • Liposome
  • Phospholipase
  • Plasma coagulation
  • Platelet aggregation
  • Polymeric liposome

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Cell Biology

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