Intraaneurysmal flow visualization by using phase-contrast magnetic resonance imaging: Feasibility study based on a geometrically realistic in vitro aneurysm model

Satoshi Tateshima, John Grinstead, Shantanu Sinha, Yih Lin Nien, Yuichi Murayama, J. Pablo Villablanca, Kazuo Tanishita, Fernando Viñuela

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Object. The aim of this study was to evaluate the feasibility of complex intraaneurysmal flow visualization with the currently available phase-contrast magnetic resonance (MR) imaging modality. Methods. A geometrically realistic in vitro aneurysm model, in which detailed flow velocity analysis had already been conducted using laser Doppler velocimetry was used for this in vitro hemodynamic simulation, so that the results of phase-contrast velocity measurements could be compared with the previous reliable results. On a 1.5-tesla unit, three orthogonal components of velocity were obtained using a standard two-dimensional fast low-angle shot flow quantification sequence. Three-dimensional (3D) intraaneurysmal flow structures recorded during one cardiac cycle were depicted in one midsagittal and three axial cross-sectional planes with the aid of gray scale phase-contrast velocity maps. Isovelocity contour maps and secondary flow vectors were also created based on the phase-contrast velocity maps by using MATLAB software. The isovelocity contours in those three axial sections could demonstrate the shapes of inward and outward flow areas and their alternation over one cardiac cycle. The secondary flow vectors demonstrated twin vortices within the outward flow area adjacent to the boundary layer of inward and outward flow in all axial planes. Conclusions. The phase-contrast MR imaging method was able to depict the complex 3D intraaneurysmal flow structures in the in vitro aneurysm model. Detailed 3D intraaneurysmal flow information will be obtainable in vivo after improvements are made in spatial resolution, which is expected in the near future. The capability to visualize intraaneurysmal flow structures directly with the use of noninvasive MR imaging technology will have a positive impact on future clinical practice.

Original languageEnglish
Pages (from-to)1041-1048
Number of pages8
JournalJournal of Neurosurgery
Volume100
Issue number6
Publication statusPublished - 2004 Jun
Externally publishedYes

Fingerprint

Feasibility Studies
Aneurysm
Magnetic Resonance Imaging
Laser-Doppler Flowmetry
Software
Hemodynamics
Technology
In Vitro Techniques

Keywords

  • Acrylic aneurysm model
  • Cerebral aneurysm
  • Cine phase-contrast magnetic resonance imaging
  • Hemodynamics

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Tateshima, S., Grinstead, J., Sinha, S., Nien, Y. L., Murayama, Y., Villablanca, J. P., ... Viñuela, F. (2004). Intraaneurysmal flow visualization by using phase-contrast magnetic resonance imaging: Feasibility study based on a geometrically realistic in vitro aneurysm model. Journal of Neurosurgery, 100(6), 1041-1048.

Intraaneurysmal flow visualization by using phase-contrast magnetic resonance imaging : Feasibility study based on a geometrically realistic in vitro aneurysm model. / Tateshima, Satoshi; Grinstead, John; Sinha, Shantanu; Nien, Yih Lin; Murayama, Yuichi; Villablanca, J. Pablo; Tanishita, Kazuo; Viñuela, Fernando.

In: Journal of Neurosurgery, Vol. 100, No. 6, 06.2004, p. 1041-1048.

Research output: Contribution to journalArticle

Tateshima, S, Grinstead, J, Sinha, S, Nien, YL, Murayama, Y, Villablanca, JP, Tanishita, K & Viñuela, F 2004, 'Intraaneurysmal flow visualization by using phase-contrast magnetic resonance imaging: Feasibility study based on a geometrically realistic in vitro aneurysm model', Journal of Neurosurgery, vol. 100, no. 6, pp. 1041-1048.
Tateshima, Satoshi ; Grinstead, John ; Sinha, Shantanu ; Nien, Yih Lin ; Murayama, Yuichi ; Villablanca, J. Pablo ; Tanishita, Kazuo ; Viñuela, Fernando. / Intraaneurysmal flow visualization by using phase-contrast magnetic resonance imaging : Feasibility study based on a geometrically realistic in vitro aneurysm model. In: Journal of Neurosurgery. 2004 ; Vol. 100, No. 6. pp. 1041-1048.
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abstract = "Object. The aim of this study was to evaluate the feasibility of complex intraaneurysmal flow visualization with the currently available phase-contrast magnetic resonance (MR) imaging modality. Methods. A geometrically realistic in vitro aneurysm model, in which detailed flow velocity analysis had already been conducted using laser Doppler velocimetry was used for this in vitro hemodynamic simulation, so that the results of phase-contrast velocity measurements could be compared with the previous reliable results. On a 1.5-tesla unit, three orthogonal components of velocity were obtained using a standard two-dimensional fast low-angle shot flow quantification sequence. Three-dimensional (3D) intraaneurysmal flow structures recorded during one cardiac cycle were depicted in one midsagittal and three axial cross-sectional planes with the aid of gray scale phase-contrast velocity maps. Isovelocity contour maps and secondary flow vectors were also created based on the phase-contrast velocity maps by using MATLAB software. The isovelocity contours in those three axial sections could demonstrate the shapes of inward and outward flow areas and their alternation over one cardiac cycle. The secondary flow vectors demonstrated twin vortices within the outward flow area adjacent to the boundary layer of inward and outward flow in all axial planes. Conclusions. The phase-contrast MR imaging method was able to depict the complex 3D intraaneurysmal flow structures in the in vitro aneurysm model. Detailed 3D intraaneurysmal flow information will be obtainable in vivo after improvements are made in spatial resolution, which is expected in the near future. The capability to visualize intraaneurysmal flow structures directly with the use of noninvasive MR imaging technology will have a positive impact on future clinical practice.",
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AU - Nien, Yih Lin

AU - Murayama, Yuichi

AU - Villablanca, J. Pablo

AU - Tanishita, Kazuo

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