Intramolecular C-H Alkenylation of N-Alkynylindoles: Exo and Endo Selective Cyclization According to the Choice of Metal Catalyst

Takanori Shibata, Takumi Baba, Hideaki Takano, Stephen Kyalo Kanyiva

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

The intramolecular reaction of 3-acetyl-N-alkynylindoles proceeded via C-H bond cleavage at the C2 position. Iridium and rhodium catalysts selectively promoted 6-exo-dig and 7-endo-dig cyclization, respectively, and N-fused tricyclic compounds were obtained.

Original languageEnglish
JournalAdvanced Synthesis and Catalysis
DOIs
Publication statusAccepted/In press - 2017

Keywords

  • Alkenylation
  • C-H activation
  • Indoles
  • Iridium
  • Rhodium

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

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