Investigation on the mechanical characteristics of porcine amniotic membrane by uniaxial tensile test

Masato Kikuchi, Zhonggang Feng, Tadashi Kosawada, Daisuke Sato, Takao Nakamura, Mitsuo Umezu

    Research output: Contribution to journalArticle

    1 Citation (Scopus)

    Abstract

    Amniotic membrane (AM) is utilized in tissue engineering due to its advantages such as immune tolerance. However its mechanical characteristics has not been thoroughly investigated. In this study, we employed uniaxial tensile apparatus to investigate the directionality, viscoelasticity, and strength of porcine AM. The experimental results show that AM is isotropic but heterogeneous. The strength of the AM near placenta is 2.3±1.0 [MPa], higher than those of all other portions. The coefficients of stress relaxation of the AM near placenta (λ<inf>1</inf>=14.7±4.7 [s]; λ<inf>2</inf>=37.3±5.7 [s]) is also the largest.

    Original languageEnglish
    Pages (from-to)O-239-O-240
    JournalTransactions of Japanese Society for Medical and Biological Engineering
    Volume52
    DOIs
    Publication statusPublished - 2014 Aug 17

    Keywords

    • Amniotic membrane
    • Nonlinear
    • Strength
    • Viscoelasticity

    ASJC Scopus subject areas

    • Biomedical Engineering

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