The low power consumption in mW of the IEEE802.15.4/ZigBee standard is one of its feature, even though it requires the exchange of batteries. The cost of battery exchange for wireless sensors is considered as one of the critical problems for wireless sensor networks (WSN). Sediment microbial fuel cell (SMFC) can be a promising technology to replace conventional energy sources by renewable energy sources for wireless sensors, which has the potential to supply sustainable WSN without a replacement of batteries. However, SMFC cannot drive a microcontroller directly since it only provides ultra-low voltage and ultra-low current. In addition, from a general perspective, SMFC is costly to build for wireless sensors due to its materials costs. Considered about those challenges, this paper proposed a novel energy harvesting system for the ZigBee network which consists of the SMFC sensor and a power management circuit to accumulate adequate energy for load. Intermittent data transmission between the ZigBee end-device and coordinator is conducted with the designed energy harvesting system. The experimental results showed that the SMFC-powered ZigBee sensor device is eligible to enable intermittent communication in replacement of conventional battery.