The chiral Ir(I)-catalyzed intermolecular reaction of N-carbamoylpyrrole and indole derivatives with α,β-unsaturated carbonyl compounds such as crotonates proceeded with high enantioselectivity. The obtained chirally functionalized pyrroles and indoles are formal C-H conjugate adducts. The reaction mechanism was studied by deuterium labeling experiments.
|Number of pages||5|
|Publication status||Published - 2021 Dec 3|
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry