TY - JOUR
T1 - Kinanthraquinone, a new anthraquinone carboxamide isolated from Streptomyces reveromyceticus SN-593-44
AU - Takagi, Hiroshi
AU - Nogawa, Toshihiko
AU - Futamura, Yushi
AU - Takahashi, Shunji
AU - Osada, Hiroyuki
N1 - Publisher Copyright:
© 2018 The Author(s) [YEAR], under exclusive licence to the Japan Antibiotics Research Association.
PY - 2018/3/1
Y1 - 2018/3/1
N2 - A new anthraquinone derivative, kinanthraquinone (1) was isolated from Streptomyces reveromyceticus SN-593-44. Its structure was determined by the combination of spectroscopic methods including NMR and MS. Kinanthraquinone had a characteristic carboxamide group and was a rare class of metabolite as an anthraquinone derivative isolated from microbes. It showed moderate cytotoxocity against HL-60 and src ts -NRK cell with IC 50 value of 7.9 and 10 μM, respectively.
AB - A new anthraquinone derivative, kinanthraquinone (1) was isolated from Streptomyces reveromyceticus SN-593-44. Its structure was determined by the combination of spectroscopic methods including NMR and MS. Kinanthraquinone had a characteristic carboxamide group and was a rare class of metabolite as an anthraquinone derivative isolated from microbes. It showed moderate cytotoxocity against HL-60 and src ts -NRK cell with IC 50 value of 7.9 and 10 μM, respectively.
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U2 - 10.1038/s41429-017-0020-0
DO - 10.1038/s41429-017-0020-0
M3 - Article
C2 - 29410517
AN - SCOPUS:85041623821
SN - 0021-8820
VL - 71
SP - 480
EP - 482
JO - Journal of Antibiotics
JF - Journal of Antibiotics
IS - 4
ER -