TY - JOUR
T1 - Large nonlinear effect observed in the enantiomeric excess of proline in solution and that in the solid state
AU - Hayashi, Yujiro
AU - Matsuzawa, Masayoshi
AU - Yamaguchi, Junichiro
AU - Yonehara, Sayaka
AU - Matsumoto, Yasunobu
AU - Shoji, Mitsuru
AU - Hashizume, Daisuke
AU - Koshino, Hiroyuki
PY - 2006/7/10
Y1 - 2006/7/10
N2 - (Chemical Equation Presented) A clue to the origin of chirality? A solution of proline with high enantiomeric excess (85-99% ee) was obtained from solid proline of only 10% ee through novel dissolution and crystallization processes (see scheme). This observation may be an explanation for the origin of chirality on Earth.
AB - (Chemical Equation Presented) A clue to the origin of chirality? A solution of proline with high enantiomeric excess (85-99% ee) was obtained from solid proline of only 10% ee through novel dissolution and crystallization processes (see scheme). This observation may be an explanation for the origin of chirality on Earth.
KW - Amino acids
KW - Asymmetric catalysis
KW - Carbohydrates
KW - Chirality
KW - Proline
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U2 - 10.1002/anie.200601506
DO - 10.1002/anie.200601506
M3 - Article
C2 - 16819754
AN - SCOPUS:33746294399
SN - 1433-7851
VL - 45
SP - 4593
EP - 4597
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
IS - 28
ER -